Wiltshire S - Search Results

1

Examining the candidacy of ghrelin as a gene responsible for variation in adult stature in a United Kingdom population with type 2 diabetes.

Gueorguiev M, Wiltshire S, Garcia EA, Mein C, Lecoeur C, Kristen B, Allotey R, Hattersley AT, Walker M, O'rahilly S, Froguel P, Grossman AB, McCarthy MI, Hitman GA, Korbonits M. Gueorguiev M, et al. Among authors: wiltshire s. J Clin Endocrinol Metab. 2007 Jun;92(6):2201-4. doi: 10.1210/jc.2006-2657. Epub 2007 Mar 27. J Clin Endocrinol Metab. 2007. PMID: 17389697

2

Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome.

Haddad L, Evans JC, Gharani N, Robertson C, Rush K, Wiltshire S, Frayling TM, Wilkin TJ, Demaine A, Millward A, Hattersley AT, Conway G, Cox NJ, Bell GI, Franks S, McCarthy MI. Haddad L, et al. Among authors: wiltshire s. J Clin Endocrinol Metab. 2002 Jun;87(6):2606-10. doi: 10.1210/jcem.87.6.8608. J Clin Endocrinol Metab. 2002. PMID: 12050223

3

Significant linkage of BMI to chromosome 10p in the U.K. population and evaluation of GAD2 as a positional candidate.

Groves CJ, Zeggini E, Walker M, Hitman GA, Levy JC, O'Rahilly S, Hattersley AT, McCarthy MI, Wiltshire S. Groves CJ, et al. Among authors: wiltshire s. Diabetes. 2006 Jun;55(6):1884-9. doi: 10.2337/db05-1674. Diabetes. 2006. PMID: 16731858

4

Evidence for linkage of stature to chromosome 3p26 in a large U.K. Family data set ascertained for type 2 diabetes.

Wiltshire S, Frayling TM, Hattersley AT, Hitman GA, Walker M, Levy JC, O'Rahilly S, Groves CJ, Menzel S, Cardon LR, McCarthy MI. Wiltshire S, et al. Am J Hum Genet. 2002 Feb;70(2):543-6. doi: 10.1086/338760. Epub 2001 Dec 20. Am J Hum Genet. 2002. PMID: 11753821 Free PMC article.

5

Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility.

Groves CJ, Wiltshire S, Smedley D, Owen KR, Frayling TM, Walker M, Hitman GA, Levy JC, O'Rahilly S, Menzel S, Hattersley AT, McCarthy MI. Groves CJ, et al. Among authors: wiltshire s. Diabetes. 2003 May;52(5):1300-5. doi: 10.2337/diabetes.52.5.1300. Diabetes. 2003. PMID: 12716770

6

Association analysis of 6,736 U.K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk.

Groves CJ, Zeggini E, Minton J, Frayling TM, Weedon MN, Rayner NW, Hitman GA, Walker M, Wiltshire S, Hattersley AT, McCarthy MI. Groves CJ, et al. Among authors: wiltshire s. Diabetes. 2006 Sep;55(9):2640-4. doi: 10.2337/db06-0355. Diabetes. 2006. PMID: 16936215

7

Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism.

Liew CF, Groves CJ, Wiltshire S, Zeggini E, Frayling TM, Owen KR, Walker M, Hitman GA, Levy JC, O'rahilly S, Hattersley AT, Johnston DG, McCarthy MI. Liew CF, et al. Among authors: wiltshire s. Diabetologia. 2004 Dec;47(12):2168-75. doi: 10.1007/s00125-004-1575-4. Epub 2004 Dec 15. Diabetologia. 2004. PMID: 15662557

8

Epistasis between type 2 diabetes susceptibility Loci on chromosomes 1q21-25 and 10q23-26 in northern Europeans.

Wiltshire S, Bell JT, Groves CJ, Dina C, Hattersley AT, Frayling TM, Walker M, Hitman GA, Vaxillaire M, Farrall M, Froguel P, McCarthy MI. Wiltshire S, et al. Ann Hum Genet. 2006 Nov;70(Pt 6):726-37. doi: 10.1111/j.1469-1809.2006.00289.x. Ann Hum Genet. 2006. PMID: 17044847

9

Evaluating the results of genomewide linkage scans of complex traits by locus counting.

Wiltshire S, Cardon LR, McCarthy MI. Wiltshire S, et al. Am J Hum Genet. 2002 Nov;71(5):1175-82. doi: 10.1086/342976. Epub 2002 Sep 25. Am J Hum Genet. 2002. PMID: 12355401 Free PMC article.

10

How useful is the fine-scale mapping of complex trait linkage peaks? Evaluating the impact of additional microsatellite genotyping on the posterior probability of linkage.

Wiltshire S, Morris AP, McCarthy MI, Cardon LR. Wiltshire S, et al. Genet Epidemiol. 2005 Jan;28(1):1-10. doi: 10.1002/gepi.20023. Genet Epidemiol. 2005. PMID: 15493062

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