Scaglione KM - Search Results

1

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D, Gygi SP, Goldberg AL. Kim HT, et al. Among authors: scaglione km. J Biol Chem. 2007 Jun 15;282(24):17375-86. doi: 10.1074/jbc.M609659200. Epub 2007 Apr 10. J Biol Chem. 2007. PMID: 17426036 Free article.

2

Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1.

Deffenbaugh AE, Scaglione KM, Zhang L, Moore JM, Buranda T, Sklar LA, Skowyra D. Deffenbaugh AE, et al. Among authors: scaglione km. Cell. 2003 Sep 5;114(5):611-22. doi: 10.1016/s0092-8674(03)00641-x. Cell. 2003. PMID: 13678584 Free article.

3

SCF E3-mediated autoubiquitination negatively regulates activity of Cdc34 E2 but plays a nonessential role in the catalytic cycle in vitro and in vivo.

Scaglione KM, Bansal PK, Deffenbaugh AE, Kiss A, Moore JM, Korolev S, Cocklin R, Goebl M, Kitagawa K, Skowyra D. Scaglione KM, et al. Mol Cell Biol. 2007 Aug;27(16):5860-70. doi: 10.1128/MCB.01555-06. Epub 2007 Jun 11. Mol Cell Biol. 2007. PMID: 17562869 Free PMC article.

4

The loop-less tmCdc34 E2 mutant defective in polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2.

Lass A, Cocklin R, Scaglione KM, Skowyra M, Korolev S, Goebl M, Skowyra D. Lass A, et al. Among authors: scaglione km. Cell Div. 2011 Mar 31;6:7. doi: 10.1186/1747-1028-6-7. Cell Div. 2011. PMID: 21453497 Free PMC article.

5

The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.

Scaglione KM, Basrur V, Ashraf NS, Konen JR, Elenitoba-Johnson KS, Todi SV, Paulson HL. Scaglione KM, et al. J Biol Chem. 2013 Jun 28;288(26):18784-8. doi: 10.1074/jbc.C113.477596. Epub 2013 May 21. J Biol Chem. 2013. PMID: 23696636 Free PMC article.

6

Erratum to: The loop-less ^tmCdc34 E2 mutant defective polyubiquitination in vitro and in vivo supports yeast growth in a manner dependent on Ubp14 and Cka2.

Lass A, Cocklin R, Scaglione KM, Skowyra M, Korolev S, Goebl M, Skowyra D. Lass A, et al. Among authors: scaglione km. Cell Div. 2016 Oct 6;11:13. doi: 10.1186/s13008-016-0018-1. eCollection 2016. Cell Div. 2016. PMID: 27761151 Free PMC article.

7

The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains.

Winborn BJ, Travis SM, Todi SV, Scaglione KM, Xu P, Williams AJ, Cohen RE, Peng J, Paulson HL. Winborn BJ, et al. Among authors: scaglione km. J Biol Chem. 2008 Sep 26;283(39):26436-43. doi: 10.1074/jbc.M803692200. Epub 2008 Jul 3. J Biol Chem. 2008. PMID: 18599482 Free PMC article.

8

The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP.

Umano A, Fang K, Qu Z, Scaglione JB, Altinok S, Treadway CJ, Wick ET, Paulakonis E, Karunanayake C, Chou S, Bardakjian TM, Gonzalez-Alegre P, Page RC, Schisler JC, Brown NG, Yan D, Scaglione KM. Umano A, et al. Among authors: scaglione km. J Biol Chem. 2022 May;298(5):101899. doi: 10.1016/j.jbc.2022.101899. Epub 2022 Apr 7. J Biol Chem. 2022. PMID: 35398354 Free PMC article.

9

Loss of the Ubiquitin-conjugating Enzyme UBE2W Results in Susceptibility to Early Postnatal Lethality and Defects in Skin, Immune, and Male Reproductive Systems.

Wang B, Merillat SA, Vincent M, Huber AK, Basrur V, Mangelberger D, Zeng L, Elenitoba-Johnson K, Miller RA, Irani DN, Dlugosz AA, Schnell S, Scaglione KM, Paulson HL. Wang B, et al. Among authors: scaglione km. J Biol Chem. 2016 Feb 5;291(6):3030-42. doi: 10.1074/jbc.M115.676601. Epub 2015 Nov 24. J Biol Chem. 2016. PMID: 26601958 Free PMC article.

10

USP5 Is Dispensable for Monoubiquitin Maintenance in Drosophila.

Ristic G, Tsou WL, Guzi E, Kanack AJ, Scaglione KM, Todi SV. Ristic G, et al. Among authors: scaglione km. J Biol Chem. 2016 Apr 22;291(17):9161-72. doi: 10.1074/jbc.M115.703504. Epub 2016 Feb 25. J Biol Chem. 2016. PMID: 26917723 Free PMC article.

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