Doss G - Search Results

1

Absorption, metabolism, and excretion of [(14)C]MK-0524, a prostaglandin D(2) receptor antagonist, in humans.

Karanam B, Madeira M, Bradley S, Wenning L, Desai R, Soli E, Schenk D, Jones A, Dean B, Doss G, Garrett G, Crumley T, Nirula A, Lai E. Karanam B, et al. Among authors: doss g. Drug Metab Dispos. 2007 Jul;35(7):1196-202. doi: 10.1124/dmd.107.014696. Epub 2007 Apr 12. Drug Metab Dispos. 2007. PMID: 17431030 Clinical Trial.

2

Pharmacokinetics, metabolism, and excretion of anacetrapib, a novel inhibitor of the cholesteryl ester transfer protein, in rats and rhesus monkeys.

Tan EY, Hartmann G, Chen Q, Pereira A, Bradley S, Doss G, Zhang AS, Ho JZ, Braun MP, Dean DC, Tang W, Kumar S. Tan EY, et al. Among authors: doss g. Drug Metab Dispos. 2010 Mar;38(3):459-73. doi: 10.1124/dmd.109.028696. Epub 2009 Dec 16. Drug Metab Dispos. 2010. PMID: 20016052

3

In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl)-phenyl] methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. II. Identification of metabolites by liquid chromatography-tandem mass spectrometry.

Liu DQ, Karanam BV, Doss GA, Sidler RR, Vincent SH, Hop CE. Liu DQ, et al. Drug Metab Dispos. 2004 Sep;32(9):1023-31. doi: 10.1124/dmd.104.000059. Drug Metab Dispos. 2004. PMID: 15319345

4

The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs.

Huskey SE, Dean BJ, Doss GA, Wang Z, Hop CE, Anari R, Finke PE, Robichaud AJ, Zhang M, Wang B, Strauss JR, Cunningham PK, Feeney WP, Franklin RB, Baillie TA, Chiu SH. Huskey SE, et al. Drug Metab Dispos. 2004 Feb;32(2):246-58. doi: 10.1124/dmd.32.2.246. Drug Metab Dispos. 2004. PMID: 14744948

5

Identification and metabolism of a novel dihydrohydroxy-S-glutathionyl conjugate of a peroxisome proliferator-activated receptor agonist, MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], in rats.

Reddy VB, Doss GA, Creighton M, Kochansky CJ, Vincent SH, Franklin RB, Karanam BV. Reddy VB, et al. Among authors: doss ga. Drug Metab Dispos. 2004 Oct;32(10):1154-61. doi: 10.1124/dmd.104.000240. Epub 2004 Jun 30. Drug Metab Dispos. 2004. PMID: 15229171

6

Glutathione S-transferase catalyzed desulfonylation of a sulfonylfuropyridine.

Bateman TJ, Debenham JS, Madsen-Duggan C, Toupence RB, Walsh TF, Truong Q, Bradley SA, Doss GA, Kumar S, Reddy VB. Bateman TJ, et al. Among authors: doss ga. Drug Metab Dispos. 2010 Jan;38(1):108-14. doi: 10.1124/dmd.109.029801. Drug Metab Dispos. 2010. PMID: 19797605

7

Orally active inhibitors of human leukocyte elastase. II. Disposition of L-694,458 in rats and rhesus monkeys.

Vincent SH, Painter SK, Luffer-Atlas D, Karanam BV, McGowan E, Cioffe C, Doss G, Chiu SH. Vincent SH, et al. Among authors: doss g. Drug Metab Dispos. 1997 Aug;25(8):932-9. Drug Metab Dispos. 1997. PMID: 9280401

8

The absorption, distribution, metabolism and excretion of rofecoxib, a potent and selective cyclooxygenase-2 inhibitor, in rats and dogs.

Halpin RA, Geer LA, Zhang KE, Marks TM, Dean DC, Jones AN, Melillo D, Doss G, Vyas KP. Halpin RA, et al. Among authors: doss g. Drug Metab Dispos. 2000 Oct;28(10):1244-54. Drug Metab Dispos. 2000. PMID: 10997947

9

Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques.

Baillie TA, Halpin RA, Matuszewski BK, Geer LA, Chavez-Eng CM, Dean D, Braun M, Doss G, Jones A, Marks T, Melillo D, Vyas KP. Baillie TA, et al. Among authors: doss g. Drug Metab Dispos. 2001 Dec;29(12):1614-28. Drug Metab Dispos. 2001. PMID: 11717181

10

Glucuronidation, oxidative metabolism, and bioactivation of enterolactone in rhesus monkeys.

Dean B, Chang S, Doss GA, King C, Thomas PE. Dean B, et al. Arch Biochem Biophys. 2004 Sep 15;429(2):244-51. doi: 10.1016/j.abb.2004.06.023. Arch Biochem Biophys. 2004. PMID: 15313229

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