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Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate.
Cancer Res. 2007 Apr 15;67(8):3767-76. doi: 10.1158/0008-5472.CAN-06-3065.
Cancer Res. 2007.
PMID: 17440090
The effects of vinflunine, vinorelbine, and vinblastine on centromere dynamics.
Okouneva T, Hill BT, Wilson L, Jordan MA.
Okouneva T, et al.
Mol Cancer Ther. 2003 May;2(5):427-36.
Mol Cancer Ther. 2003.
PMID: 12748304
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The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth.
Jordan MA, Kamath K, Manna T, Okouneva T, Miller HP, Davis C, Littlefield BA, Wilson L.
Jordan MA, et al. Among authors: okouneva t.
Mol Cancer Ther. 2005 Jul;4(7):1086-95. doi: 10.1158/1535-7163.MCT-04-0345.
Mol Cancer Ther. 2005.
PMID: 16020666
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2-Methoxyestradiol suppresses microtubule dynamics and arrests mitosis without depolymerizing microtubules.
Kamath K, Okouneva T, Larson G, Panda D, Wilson L, Jordan MA.
Kamath K, et al. Among authors: okouneva t.
Mol Cancer Ther. 2006 Sep;5(9):2225-33. doi: 10.1158/1535-7163.MCT-06-0113.
Mol Cancer Ther. 2006.
PMID: 16985056
Free article.
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Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase.
Okouneva T, Azarenko O, Wilson L, Littlefield BA, Jordan MA.
Okouneva T, et al.
Mol Cancer Ther. 2008 Jul;7(7):2003-11. doi: 10.1158/1535-7163.MCT-08-0095.
Mol Cancer Ther. 2008.
PMID: 18645010
Free PMC article.
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Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by sulforaphane.
Azarenko O, Okouneva T, Singletary KW, Jordan MA, Wilson L.
Azarenko O, et al. Among authors: okouneva t.
Carcinogenesis. 2008 Dec;29(12):2360-8. doi: 10.1093/carcin/bgn241. Epub 2008 Oct 23.
Carcinogenesis. 2008.
PMID: 18952594
Free PMC article.
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Effects of tetramethoxystilbene on hormone-resistant breast cancer cells: biological and biochemical mechanisms of action.
Park H, Aiyar SE, Fan P, Wang J, Yue W, Okouneva T, Cox C, Jordan MA, Demers L, Cho H, Kim S, Song RX, Santen RJ.
Park H, et al. Among authors: okouneva t.
Cancer Res. 2007 Jun 15;67(12):5717-26. doi: 10.1158/0008-5472.CAN-07-0056.
Cancer Res. 2007.
PMID: 17575138
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