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Genetics of healthy aging in Europe: the EU-integrated project GEHA (GEnetics of Healthy Aging).
Franceschi C, Bezrukov V, Blanché H, Bolund L, Christensen K, de Benedictis G, Deiana L, Gonos E, Hervonen A, Yang H, Jeune B, Kirkwood TB, Kristensen P, Leon A, Pelicci PG, Peltonen L, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Sikora E, Slagboom PE, Spazzafumo L, Stazi MA, Toussaint O, Vaupel JW. Franceschi C, et al. Among authors: hervonen a. Ann N Y Acad Sci. 2007 Apr;1100:21-45. doi: 10.1196/annals.1395.003. Ann N Y Acad Sci. 2007. PMID: 17460163 Review.
How to classify the oldest old according to their health status: a study on 1160 subjects belonging to 552 90+ Italian sib-ships characterized by familial longevity recruited within the GEHA EU Project.
Cevenini E, Cotichini R, Stazi MA, Toccaceli V, Scurti M, Mari V, Berardelli M, Passarino G, Jeune B, Franceschi C; GEHA Project Consortium. Cevenini E, et al. Mech Ageing Dev. 2013 Nov-Dec;134(11-12):560-9. doi: 10.1016/j.mad.2013.11.001. Epub 2013 Nov 20. Mech Ageing Dev. 2013. PMID: 24269880
The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific.
Raule N, Sevini F, Li S, Barbieri A, Tallaro F, Lomartire L, Vianello D, Montesanto A, Moilanen JS, Bezrukov V, Blanché H, Hervonen A, Christensen K, Deiana L, Gonos ES, Kirkwood TB, Kristensen P, Leon A, Pelicci PG, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Sikora E, Eline Slagboom P, Spazzafumo L, Antonietta Stazi M, Toussaint O, Vaupel JW, Rose G, Majamaa K, Perola M, Johnson TE, Bolund L, Yang H, Passarino G, Franceschi C. Raule N, et al. Among authors: hervonen a. Aging Cell. 2014 Jun;13(3):401-7. doi: 10.1111/acel.12186. Epub 2013 Dec 17. Aging Cell. 2014. PMID: 24341918 Free PMC article.
MARK-AGE biomarkers of ageing.
Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, Kristensen P, Griffiths HR, Libert C, Grune T, Breusing N, Simm A, Franceschi C, Capri M, Talbot D, Caiafa P, Friguet B, Slagboom PE, Hervonen A, Hurme M, Aspinall R. Bürkle A, et al. Among authors: hervonen a. Mech Ageing Dev. 2015 Nov;151:2-12. doi: 10.1016/j.mad.2015.03.006. Epub 2015 Mar 24. Mech Ageing Dev. 2015. PMID: 25818235 Free article. Review.
Design, recruitment, logistics, and data management of the GEHA (Genetics of Healthy Ageing) project.
Skytthe A, Valensin S, Jeune B, Cevenini E, Balard F, Beekman M, Bezrukov V, Blanche H, Bolund L, Broczek K, Carru C, Christensen K, Christiansen L, Collerton JC, Cotichini R, de Craen AJ, Dato S, Davies K, De Benedictis G, Deiana L, Flachsbart F, Gampe J, Gilbault C, Gonos ES, Haimes E, Hervonen A, Hurme MA, Janiszewska D, Jylhä M, Kirkwood TB, Kristensen P, Laiho P, Leon A, Marchisio A, Masciulli R, Nebel A, Passarino G, Pelicci G, Peltonen L, Perola M, Poulain M, Rea IM, Remacle J, Robine JM, Schreiber S, Scurti M, Sevini F, Sikora E, Skouteri A, Slagboom PE, Spazzafumo L, Stazi MA, Toccaceli V, Toussaint O, Törnwall O, Vaupel JW, Voutetakis K, Franceschi C; GEHA consortium. Skytthe A, et al. Among authors: hervonen a. Exp Gerontol. 2011 Nov;46(11):934-45. doi: 10.1016/j.exger.2011.08.005. Epub 2011 Aug 16. Exp Gerontol. 2011. PMID: 21871552 Free PMC article.
MARK-AGE population: From the human model to new insights.
Capri M, Moreno-Villanueva M, Cevenini E, Pini E, Scurti M, Borelli V, Palmas MG, Zoli M, Schön C, Siepelmeyer A, Bernhardt J, Fiegl S, Zondag G, de Craen AJ, Hervonen A, Hurme M, Sikora E, Gonos ES, Voutetakis K, Toussaint O, Debacq-Chainiaux F, Grubeck-Loebenstein B, Bürkle A, Franceschi C. Capri M, et al. Among authors: hervonen a. Mech Ageing Dev. 2015 Nov;151:13-7. doi: 10.1016/j.mad.2015.03.010. Epub 2015 Apr 2. Mech Ageing Dev. 2015. PMID: 25843237 Free article. Review. No abstract available.
Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study.
Ciccarone F, Malavolta M, Calabrese R, Guastafierro T, Bacalini MG, Reale A, Franceschi C, Capri M, Hervonen A, Hurme M, Grubeck-Loebenstein B, Koller B, Bernhardt J, Schӧn C, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé M, Moreno-Villanueva M, Sindlinger T, Bürkle A, Zampieri M, Caiafa P. Ciccarone F, et al. Among authors: hervonen a. Aging Cell. 2016 Aug;15(4):755-65. doi: 10.1111/acel.12485. Epub 2016 May 11. Aging Cell. 2016. PMID: 27169697 Free PMC article.
Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study.
Valentini E, Zampieri M, Malavolta M, Bacalini MG, Calabrese R, Guastafierro T, Reale A, Franceschi C, Hervonen A, Koller B, Bernhardt J, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé ME, Moreno-Villanueva M, Sindlinger T, Bürkle A, Ciccarone F, Caiafa P. Valentini E, et al. Among authors: hervonen a. Aging (Albany NY). 2016 Aug 29;8(9):1896-1922. doi: 10.18632/aging.101022. Aging (Albany NY). 2016. PMID: 27587280 Free PMC article.
249 results