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AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
Batchelor TT, Sorensen AG, di Tomaso E, Zhang WT, Duda DG, Cohen KS, Kozak KR, Cahill DP, Chen PJ, Zhu M, Ancukiewicz M, Mrugala MM, Plotkin S, Drappatz J, Louis DN, Ivy P, Scadden DT, Benner T, Loeffler JS, Wen PY, Jain RK. Batchelor TT, et al. Cancer Cell. 2007 Jan;11(1):83-95. doi: 10.1016/j.ccr.2006.11.021. Cancer Cell. 2007. PMID: 17222792 Free PMC article. Clinical Trial.
Angiogenesis in brain tumours.
Jain RK, di Tomaso E, Duda DG, Loeffler JS, Sorensen AG, Batchelor TT. Jain RK, et al. Among authors: batchelor tt. Nat Rev Neurosci. 2007 Aug;8(8):610-22. doi: 10.1038/nrn2175. Nat Rev Neurosci. 2007. PMID: 17643088 Review.
Antiangiogenic agents for the treatment of glioblastoma.
Gerstner ER, Duda DG, di Tomaso E, Sorensen G, Jain RK, Batchelor TT. Gerstner ER, et al. Among authors: batchelor tt. Expert Opin Investig Drugs. 2007 Dec;16(12):1895-908. doi: 10.1517/13543784.16.12.1895. Expert Opin Investig Drugs. 2007. PMID: 18041999 Review.
Response criteria for glioma.
Sorensen AG, Batchelor TT, Wen PY, Zhang WT, Jain RK. Sorensen AG, et al. Among authors: batchelor tt. Nat Clin Pract Oncol. 2008 Nov;5(11):634-44. doi: 10.1038/ncponc1204. Epub 2008 Aug 19. Nat Clin Pract Oncol. 2008. PMID: 18711427 Free PMC article. Review.
Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice.
Kamoun WS, Ley CD, Farrar CT, Duyverman AM, Lahdenranta J, Lacorre DA, Batchelor TT, di Tomaso E, Duda DG, Munn LL, Fukumura D, Sorensen AG, Jain RK. Kamoun WS, et al. Among authors: batchelor tt. J Clin Oncol. 2009 May 20;27(15):2542-52. doi: 10.1200/JCO.2008.19.9356. Epub 2009 Mar 30. J Clin Oncol. 2009. PMID: 19332720 Free PMC article.
Anti-vascular endothelial growth factor therapy for malignant glioma.
Gerstner ER, Sorensen AG, Jain RK, Batchelor TT. Gerstner ER, et al. Among authors: batchelor tt. Curr Neurol Neurosci Rep. 2009 May;9(3):254-62. doi: 10.1007/s11910-009-0037-2. Curr Neurol Neurosci Rep. 2009. PMID: 19348715 Free PMC article. Review.
Biomarkers of response and resistance to antiangiogenic therapy.
Jain RK, Duda DG, Willett CG, Sahani DV, Zhu AX, Loeffler JS, Batchelor TT, Sorensen AG. Jain RK, et al. Among authors: batchelor tt. Nat Rev Clin Oncol. 2009 Jun;6(6):327-38. doi: 10.1038/nrclinonc.2009.63. Nat Rev Clin Oncol. 2009. PMID: 19483739 Free PMC article. Review.
335 results