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Page 1
Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors.
Holsworth DD, Jalaie M, Belliotti T, Cai C, Collard W, Ferreira S, Powell NA, Stier M, Zhang E, McConnell P, Mochalkin I, Ryan MJ, Bryant J, Li T, Kasani A, Subedi R, Maiti SN, Edmunds JJ. Holsworth DD, et al. Among authors: belliotti t. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3575-80. doi: 10.1016/j.bmcl.2007.04.052. Epub 2007 Apr 25. Bioorg Med Chem Lett. 2007. PMID: 17482464
Isoindolinone enantiomers having affinity for the dopamine D4 receptor.
Belliotti TR, Brink WA, Kesten SR, Rubin JR, Wustrow DJ, Zoski KT, Whetzel SZ, Corbin AE, Pugsley TA, Heffner TG, Wise LD. Belliotti TR, et al. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1499-502. doi: 10.1016/s0960-894x(98)00252-2. Bioorg Med Chem Lett. 1998. PMID: 9873377
Aminopyrimidines with high affinity for both serotonin and dopamine receptors.
Wustrow D, Belliotti T, Glase S, Kesten SR, Johnson D, Colbry N, Rubin R, Blackburn A, Akunne H, Corbin A, Davis MD, Georgic L, Whetzel S, Zoski K, Heffner T, Pugsley T, Wise L. Wustrow D, et al. Among authors: belliotti t. J Med Chem. 1998 Feb 26;41(5):760-71. doi: 10.1021/jm9707378. J Med Chem. 1998. PMID: 9513604
Oxadiazolone bioisosteres of pregabalin and gabapentin.
Wustrow DJ, Belliotti TR, Capiris T, Kneen CO, Bryans JS, Field MJ, Williams D, El-Kattan A, Buchholz L, Kinsora JJ, Lotarski SM, Vartanian MG, Taylor CP, Donevan SD, Thorpe AJ, Schwarz JB. Wustrow DJ, et al. Among authors: belliotti tr. Bioorg Med Chem Lett. 2009 Jan 1;19(1):247-50. doi: 10.1016/j.bmcl.2008.10.101. Epub 2008 Oct 25. Bioorg Med Chem Lett. 2009. PMID: 19010672
Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones.
Wagman AS, Cirz R, McEnroe G, Aggen J, Linsell MS, Goldblum AA, Lopez S, Gomez M, Miller G, Simons LJ, Belliotti TR, Harris CR, Poel TJ, Melnick MJ, Gaston RD, Moser HE. Wagman AS, et al. Among authors: belliotti tr. ChemMedChem. 2017 Oct 20;12(20):1687-1692. doi: 10.1002/cmdc.201700426. Epub 2017 Oct 2. ChemMedChem. 2017. PMID: 28881459