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Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors.
Bioorg Med Chem Lett. 2007 Jul 1;17(13):3575-80. doi: 10.1016/j.bmcl.2007.04.052. Epub 2007 Apr 25.
Bioorg Med Chem Lett. 2007.
PMID: 17482464
Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein.
Belliotti TR, Capiris T, Ekhato IV, Kinsora JJ, Field MJ, Heffner TG, Meltzer LT, Schwarz JB, Taylor CP, Thorpe AJ, Vartanian MG, Wise LD, Zhi-Su T, Weber ML, Wustrow DJ.
Belliotti TR, et al.
J Med Chem. 2005 Apr 7;48(7):2294-307. doi: 10.1021/jm049762l.
J Med Chem. 2005.
PMID: 15801823
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Isoindolinone enantiomers having affinity for the dopamine D4 receptor.
Belliotti TR, Brink WA, Kesten SR, Rubin JR, Wustrow DJ, Zoski KT, Whetzel SZ, Corbin AE, Pugsley TA, Heffner TG, Wise LD.
Belliotti TR, et al.
Bioorg Med Chem Lett. 1998 Jun 16;8(12):1499-502. doi: 10.1016/s0960-894x(98)00252-2.
Bioorg Med Chem Lett. 1998.
PMID: 9873377
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Aminopyrimidines with high affinity for both serotonin and dopamine receptors.
Wustrow D, Belliotti T, Glase S, Kesten SR, Johnson D, Colbry N, Rubin R, Blackburn A, Akunne H, Corbin A, Davis MD, Georgic L, Whetzel S, Zoski K, Heffner T, Pugsley T, Wise L.
Wustrow D, et al. Among authors: belliotti t.
J Med Chem. 1998 Feb 26;41(5):760-71. doi: 10.1021/jm9707378.
J Med Chem. 1998.
PMID: 9513604
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Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.
Flynn DL, Belliotti TR, Boctor AM, Connor DT, Kostlan CR, Nies DE, Ortwine DF, Schrier DJ, Sircar JC.
Flynn DL, et al. Among authors: belliotti tr.
J Med Chem. 1991 Feb;34(2):518-25. doi: 10.1021/jm00106a006.
J Med Chem. 1991.
PMID: 1847426
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Oxadiazolone bioisosteres of pregabalin and gabapentin.
Wustrow DJ, Belliotti TR, Capiris T, Kneen CO, Bryans JS, Field MJ, Williams D, El-Kattan A, Buchholz L, Kinsora JJ, Lotarski SM, Vartanian MG, Taylor CP, Donevan SD, Thorpe AJ, Schwarz JB.
Wustrow DJ, et al. Among authors: belliotti tr.
Bioorg Med Chem Lett. 2009 Jan 1;19(1):247-50. doi: 10.1016/j.bmcl.2008.10.101. Epub 2008 Oct 25.
Bioorg Med Chem Lett. 2009.
PMID: 19010672
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A series of 6- and 7-piperazinyl- and -piperidinylmethylbenzoxazinones with dopamine D4 antagonist activity: discovery of a potential atypical antipsychotic agent.
Belliotti TR, Wustrow DJ, Brink WA, Zoski KT, Shih YH, Whetzel SZ, Georgic LM, Corbin AE, Akunne HC, Heffner TG, Pugsley TA, Wise LD.
Belliotti TR, et al.
J Med Chem. 1999 Dec 16;42(25):5181-7. doi: 10.1021/jm990277d.
J Med Chem. 1999.
PMID: 10602703
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Synthesis and Microbiological Evaluation of Novel Tetracyclic Fluoroquinolones.
Wagman AS, Cirz R, McEnroe G, Aggen J, Linsell MS, Goldblum AA, Lopez S, Gomez M, Miller G, Simons LJ, Belliotti TR, Harris CR, Poel TJ, Melnick MJ, Gaston RD, Moser HE.
Wagman AS, et al. Among authors: belliotti tr.
ChemMedChem. 2017 Oct 20;12(20):1687-1692. doi: 10.1002/cmdc.201700426. Epub 2017 Oct 2.
ChemMedChem. 2017.
PMID: 28881459
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