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Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors.
Holsworth DD, Jalaie M, Belliotti T, Cai C, Collard W, Ferreira S, Powell NA, Stier M, Zhang E, McConnell P, Mochalkin I, Ryan MJ, Bryant J, Li T, Kasani A, Subedi R, Maiti SN, Edmunds JJ. Holsworth DD, et al. Among authors: collard w. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3575-80. doi: 10.1016/j.bmcl.2007.04.052. Epub 2007 Apr 25. Bioorg Med Chem Lett. 2007. PMID: 17482464
Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors.
Powell NA, Ciske FL, Cai C, Holsworth DD, Mennen K, Van Huis CA, Jalaie M, Day J, Mastronardi M, McConnell P, Mochalkin I, Zhang E, Ryan MJ, Bryant J, Collard W, Ferreira S, Gu C, Collins R, Edmunds JJ. Powell NA, et al. Among authors: collard w. Bioorg Med Chem. 2007 Sep 1;15(17):5912-49. doi: 10.1016/j.bmc.2007.05.069. Epub 2007 Jun 2. Bioorg Med Chem. 2007. PMID: 17574423
Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies.
Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach BJ, Collard WT, McGregor C, Fakhoury SA, Schaum RP, Zhou H. Casimiro-Garcia A, et al. Bioorg Med Chem. 2008 May 1;16(9):4883-907. doi: 10.1016/j.bmc.2008.03.043. Epub 2008 Mar 20. Bioorg Med Chem. 2008. PMID: 18394907
Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists.
Casimiro-Garcia A, Bigge CF, Davis JA, Padalino T, Pulaski J, Ohren JF, McConnell P, Kane CD, Royer LJ, Stevens KA, Auerbach B, Collard W, McGregor C, Song K. Casimiro-Garcia A, et al. Among authors: collard w. Bioorg Med Chem. 2009 Oct 15;17(20):7113-25. doi: 10.1016/j.bmc.2009.09.001. Epub 2009 Sep 6. Bioorg Med Chem. 2009. PMID: 19783444
In Pursuit of an Allosteric Human Tropomyosin Kinase A (hTrkA) Inhibitor for Chronic Pain.
Subramanian G, Duclos B, Johnson PD, Williams T, Ross JT, Bowen SJ, Zhu Y, White JA, Hedke C, Huczek D, Collard W, Javens C, Vairagoundar R, Respondek T, Zachary T, Maddux T, Cox MR, Kamerling S, Gonzales AJ. Subramanian G, et al. Among authors: collard w. ACS Med Chem Lett. 2021 Oct 25;12(11):1847-1852. doi: 10.1021/acsmedchemlett.1c00483. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795875 Free PMC article.
Stability of peptide-condensed plasmid DNA formulations.
Adami RC, Collard WT, Gupta SA, Kwok KY, Bonadio J, Rice KG. Adami RC, et al. Among authors: collard wt. J Pharm Sci. 1998 Jun;87(6):678-83. doi: 10.1021/js9800477. J Pharm Sci. 1998. PMID: 9607943 Free article.
26 results