Simpson JF - Search Results

1

A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol.

Zhu H, Tucker HM, Grear KE, Simpson JF, Manning AK, Cupples LA, Estus S. Zhu H, et al. Among authors: simpson jf. Hum Mol Genet. 2007 Jul 15;16(14):1765-72. doi: 10.1093/hmg/ddm124. Epub 2007 May 21. Hum Mol Genet. 2007. PMID: 17517690 Free PMC article.

2

Plasmin deficiency does not alter endogenous murine amyloid beta levels in mice.

Tucker HM, Simpson J, Kihiko-Ehmann M, Younkin LH, McGillis JP, Younkin SG, Degen JL, Estus S. Tucker HM, et al. Neurosci Lett. 2004 Sep 30;368(3):285-9. doi: 10.1016/j.neulet.2004.07.011. Neurosci Lett. 2004. PMID: 15364412

3

Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.

Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, Estus S. Zou F, et al. Among authors: simpson jf. Hum Mol Genet. 2008 Apr 1;17(7):929-35. doi: 10.1093/hmg/ddm365. Epub 2007 Dec 8. Hum Mol Genet. 2008. PMID: 18065781 Free PMC article.

4

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain.

Grear KE, Ling IF, Simpson JF, Furman JL, Simmons CR, Peterson SL, Schmitt FA, Markesbery WR, Liu Q, Crook JE, Younkin SG, Bu G, Estus S. Grear KE, et al. Among authors: simpson jf. Mol Neurodegener. 2009 Nov 4;4:46. doi: 10.1186/1750-1326-4-46. Mol Neurodegener. 2009. PMID: 19889229 Free PMC article.

5

Expression and regulation of a low-density lipoprotein receptor exon 12 splice variant.

Ling IF, Gopalraj RK, Simpson JF, Estus S. Ling IF, et al. Among authors: simpson jf. J Neurochem. 2010 Nov;115(3):614-24. doi: 10.1111/j.1471-4159.2010.06972.x. Epub 2010 Sep 28. J Neurochem. 2010. PMID: 20807319 Free PMC article.

6

Genetics of clusterin isoform expression and Alzheimer's disease risk.

Ling IF, Bhongsatiern J, Simpson JF, Fardo DW, Estus S. Ling IF, et al. Among authors: simpson jf. PLoS One. 2012;7(4):e33923. doi: 10.1371/journal.pone.0033923. Epub 2012 Apr 10. PLoS One. 2012. PMID: 22506010 Free PMC article.

7

CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.

Malik M, Simpson JF, Parikh I, Wilfred BR, Fardo DW, Nelson PT, Estus S. Malik M, et al. Among authors: simpson jf. J Neurosci. 2013 Aug 14;33(33):13320-5. doi: 10.1523/JNEUROSCI.1224-13.2013. J Neurosci. 2013. PMID: 23946390 Free PMC article.

8

Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.

Malik M, Chiles J 3rd, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S, Crane P, Younkin S, Fardo DW, Estus S. Malik M, et al. Hum Mol Genet. 2015 Jun 15;24(12):3557-70. doi: 10.1093/hmg/ddv092. Epub 2015 Mar 11. Hum Mol Genet. 2015. PMID: 25762156 Free PMC article.

9

Alzheimer's Disease Genetics and ABCA7 Splicing.

Vasquez JB, Simpson JF, Harpole R, Estus S. Vasquez JB, et al. Among authors: simpson jf. J Alzheimers Dis. 2017;59(2):633-641. doi: 10.3233/JAD-170872. J Alzheimers Dis. 2017. PMID: 28655137 Free PMC article.

10

Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer's Disease Risk Reveal a Potential Role for SIGLEC14.

Shaw BC, Katsumata Y, Simpson JF, Fardo DW, Estus S. Shaw BC, et al. Among authors: simpson jf. Genes (Basel). 2021 Jun 30;12(7):1008. doi: 10.3390/genes12071008. Genes (Basel). 2021. PMID: 34208838 Free PMC article.

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