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The fibrin-derived peptide Bbeta15-42 is cardioprotective in a pig model of myocardial ischemia-reperfusion injury.
Crit Care Med. 2007 Jul;35(7):1730-5. doi: 10.1097/01.CCM.0000269035.30231.76.
Crit Care Med. 2007.
PMID: 17522584
Clinical Trial.
Fibrin(ogen) and its fragments in the pathophysiology and treatment of myocardial infarction.
Zacharowski K, Zacharowski P, Reingruber S, Petzelbauer P.
Zacharowski K, et al. Among authors: reingruber s.
J Mol Med (Berl). 2006 Jun;84(6):469-77. doi: 10.1007/s00109-006-0051-7. Epub 2006 May 6.
J Mol Med (Berl). 2006.
PMID: 16733765
Review.
Item in Clipboard
The effects of the fibrin-derived peptide Bbeta(15-42) in acute and chronic rodent models of myocardial ischemia-reperfusion.
Zacharowski K, Zacharowski PA, Friedl P, Mastan P, Koch A, Boehm O, Rother RP, Reingruber S, Henning R, Emeis JJ, Petzelbauer P.
Zacharowski K, et al. Among authors: reingruber s.
Shock. 2007 Jun;27(6):631-7. doi: 10.1097/SHK.0b013e31802fa038.
Shock. 2007.
PMID: 17505302
Item in Clipboard
Inducible nitric oxide synthase and heme oxygenase-1 in the lung during lipopolysaccharide tolerance and cross tolerance.
Koch A, Boehm O, Zacharowski PA, Loer SA, Weimann J, Rensing H, Foster SJ, Schmidt R, Berkels R, Reingruber S, Zacharowski K.
Koch A, et al. Among authors: reingruber s.
Crit Care Med. 2007 Dec;35(12):2775-84. doi: 10.1097/01.CCM.0000288122.24212.40.
Crit Care Med. 2007.
PMID: 17901834
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Bβ(15-42) attenuates the effect of ischemia-reperfusion injury in renal transplantation.
Sörensen I, Rong S, Susnik N, Gueler F, Shushakova N, Albrecht M, Dittrich AM, von Vietinghoff S, Becker JU, Melk A, Bohlmann A, Reingruber S, Petzelbauer P, Haller H, Schmitt R.
Sörensen I, et al. Among authors: reingruber s.
J Am Soc Nephrol. 2011 Oct;22(10):1887-96. doi: 10.1681/ASN.2011010031. Epub 2011 Aug 12.
J Am Soc Nephrol. 2011.
PMID: 21841063
Free PMC article.
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Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S.
Matt U, et al. Among authors: reingruber s.
Am J Respir Crit Care Med. 2009 Dec 15;180(12):1208-17. doi: 10.1164/rccm.200904-0626OC. Epub 2009 Sep 17.
Am J Respir Crit Care Med. 2009.
PMID: 19762562
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Peptide Bbeta(15-42) preserves endothelial barrier function in shock.
Gröger M, Pasteiner W, Ignatyev G, Matt U, Knapp S, Atrasheuskaya A, Bukin E, Friedl P, Zinkl D, Hofer-Warbinek R, Zacharowski K, Petzelbauer P, Reingruber S.
Gröger M, et al. Among authors: reingruber s.
PLoS One. 2009;4(4):e5391. doi: 10.1371/journal.pone.0005391. Epub 2009 Apr 29.
PLoS One. 2009.
PMID: 19401765
Free PMC article.
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