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GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A, Heward CB, Ravid R, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Kukull W, Papassotiropoulos A, Stephan DA. Reiman EM, et al. Among authors: dunckley t. Neuron. 2007 Jun 7;54(5):713-20. doi: 10.1016/j.neuron.2007.05.022. Neuron. 2007. PMID: 17553421 Free PMC article.
Gene expression correlates of neurofibrillary tangles in Alzheimer's disease.
Dunckley T, Beach TG, Ramsey KE, Grover A, Mastroeni D, Walker DG, LaFleur BJ, Coon KD, Brown KM, Caselli R, Kukull W, Higdon R, McKeel D, Morris JC, Hulette C, Schmechel D, Reiman EM, Rogers J, Stephan DA. Dunckley T, et al. Neurobiol Aging. 2006 Oct;27(10):1359-71. doi: 10.1016/j.neurobiolaging.2005.08.013. Epub 2005 Oct 19. Neurobiol Aging. 2006. PMID: 16242812 Free PMC article. Clinical Trial.
Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons.
Liang WS, Reiman EM, Valla J, Dunckley T, Beach TG, Grover A, Niedzielko TL, Schneider LE, Mastroeni D, Caselli R, Kukull W, Morris JC, Hulette CM, Schmechel D, Rogers J, Stephan DA. Liang WS, et al. Among authors: dunckley t. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4441-6. doi: 10.1073/pnas.0709259105. Epub 2008 Mar 10. Proc Natl Acad Sci U S A. 2008. PMID: 18332434 Free PMC article.
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, Beach TG, Mastroeni D, Grover A, Ravid R, Sando SB, Aasly JO, Heun R, Jessen F, Kölsch H, Rogers J, Hutton ML, Melquist S, Petersen RC, Alexander GE, Caselli RJ, Papassotiropoulos A, Stephan DA, Huentelman MJ. Corneveaux JJ, et al. Among authors: dunckley t. Neurobiol Aging. 2010 Jun;31(6):901-9. doi: 10.1016/j.neurobiolaging.2008.07.014. Epub 2008 Sep 13. Neurobiol Aging. 2010. PMID: 18789830 Free PMC article.
Association between GAB2 haplotype and higher glucose metabolism in Alzheimer's disease-affected brain regions in cognitively normal APOEε4 carriers.
Liang WS, Chen K, Lee W, Sidhar K, Corneveaux JJ, Allen AN, Myers A, Villa S, Meechoovet B, Pruzin J, Bandy D, Fleisher AS, Langbaum JB, Huentelman MJ, Jensen K, Dunckley T, Caselli RJ, Kaib S, Reiman EM. Liang WS, et al. Among authors: dunckley t. Neuroimage. 2011 Feb 1;54(3):1896-902. doi: 10.1016/j.neuroimage.2010.09.066. Epub 2010 Oct 1. Neuroimage. 2011. PMID: 20888920 Free PMC article.
Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology.
Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA. Liang WS, et al. Among authors: dunckley t. Neurobiol Aging. 2010 Apr;31(4):549-66. doi: 10.1016/j.neurobiolaging.2008.05.013. Epub 2008 Jun 24. Neurobiol Aging. 2010. PMID: 18572275 Free PMC article.
Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing.
Coon KD, Valla J, Szelinger S, Schneider LE, Niedzielko TL, Brown KM, Pearson JV, Halperin R, Dunckley T, Papassotiropoulos A, Caselli RJ, Reiman EM, Stephan DA. Coon KD, et al. Among authors: dunckley t. Mitochondrion. 2006 Aug;6(4):194-210. doi: 10.1016/j.mito.2006.07.002. Epub 2006 Jul 21. Mitochondrion. 2006. PMID: 16920408
50 results