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Biological effects of COMT haplotypes and psychosis risk in 22q11.2 deletion syndrome.
Gothelf D, Law AJ, Frisch A, Chen J, Zarchi O, Michaelovsky E, Ren-Patterson R, Lipska BK, Carmel M, Kolachana B, Weizman A, Weinberger DR. Gothelf D, et al. Among authors: chen j. Biol Psychiatry. 2014 Mar 1;75(5):406-13. doi: 10.1016/j.biopsych.2013.07.021. Epub 2013 Aug 28. Biol Psychiatry. 2014. PMID: 23992923 Free PMC article.
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia.
Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V, Lipska BK, Hyde TM, Song J, Rujescu D, Giegling I, Mayilyan K, Proust MJ, Soghoyan A, Caforio G, Callicott JH, Bertolino A, Meyer-Lindenberg A, Chang J, Ji Y, Egan MF, Goldberg TE, Kleinman JE, Lu B, Weinberger DR. Huffaker SJ, et al. Among authors: chen j. Nat Med. 2009 May;15(5):509-18. doi: 10.1038/nm.1962. Epub 2009 May 3. Nat Med. 2009. PMID: 19412172 Free PMC article.
Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity.
Barkus C, Korn C, Stumpenhorst K, Laatikainen LM, Ballard D, Lee S, Sharp T, Harrison PJ, Bannerman DM, Weinberger DR, Chen J, Tunbridge EM. Barkus C, et al. Among authors: chen j. Neuropsychopharmacology. 2016 Dec;41(13):3060-3069. doi: 10.1038/npp.2016.119. Epub 2016 Jul 8. Neuropsychopharmacology. 2016. PMID: 27388330 Free PMC article.
KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia.
Carr GV, Chen J, Yang F, Ren M, Yuan P, Tian Q, Bebensee A, Zhang GY, Du J, Glineburg P, Xun R, Akhile O, Akuma D, Pickel J, Barrow JC, Papaleo F, Weinberger DR. Carr GV, et al. Among authors: chen j. Mol Psychiatry. 2016 Nov;21(11):1517-1526. doi: 10.1038/mp.2015.219. Epub 2016 Feb 9. Mol Psychiatry. 2016. PMID: 26857598 Free PMC article.
128,726 results
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