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SAR of a novel 'Anthranilamide Like' series of VEGFR-2, multi protein kinase inhibitors for the treatment of cancer.
Wickens P, Kluender H, Dixon J, Brennan C, Achebe F, Bacchiocchi A, Bankston D, Bierer D, Brands M, Braun D, Brown MS, Chuang CY, Dumas J, Enyedy I, Hofilena G, Hong Z, Housley T, Jones B, Khire U, Kreiman C, Kumarasinghe E, Lowinger T, Ott-Morgan R, Perkins L, Phillips B, Schoenleber R, Scott WJ, Sheeler R, Redman A, Sun X, Taylor I, Wang L, Wilhelm S, Zhang X, Zhang M, Sullivan E, Carter C, Miglarese M, Levy J. Wickens P, et al. Among authors: phillips b. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4378-81. doi: 10.1016/j.bmcl.2007.02.075. Epub 2007 Mar 3. Bioorg Med Chem Lett. 2007. PMID: 17574417
Identification and SAR for a selective, nonpeptidyl thrombin inhibitor.
Naylor-Olsen AM, Ponticello GS, Lewis SD, Mulichak AM, Chen Z, Habecker CN, Phillips BT, Sanders WM, Tucker TJ, Shafer JA, Vacca JP. Naylor-Olsen AM, et al. Among authors: phillips bt. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1697-702. doi: 10.1016/s0960-894x(98)00296-0. Bioorg Med Chem Lett. 1998. PMID: 9873418
4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)- ethyl]-6-methanesulfonamidospiro[(2H)-1-benzopyran-2,4'-piperidin]-4-on e (L-691,121).
Elliott JM, Selnick HG, Claremon DA, Baldwin JJ, Buhrow SA, Butcher JW, Habecker CN, King SW, Lynch JJ Jr, Phillips BT, et al. Elliott JM, et al. Among authors: phillips bt. J Med Chem. 1992 Oct 16;35(21):3973-6. doi: 10.1021/jm00099a028. J Med Chem. 1992. PMID: 1433205 No abstract available.
Highly potent HCV NS4B inhibitors with activity against multiple genotypes.
Phillips B, Cai R, Delaney W, Du Z, Ji M, Jin H, Lee J, Li J, Niedziela-Majka A, Mish M, Pyun HJ, Saugier J, Tirunagari N, Wang J, Yang H, Wu Q, Sheng C, Zonte C. Phillips B, et al. J Med Chem. 2014 Mar 13;57(5):2161-6. doi: 10.1021/jm401646w. Epub 2014 Feb 18. J Med Chem. 2014. PMID: 24512292
Inhibitors of gastric acid secretion: 3,4-diamino-1,2,5-thiadiazole 1-oxides and 1,1-dioxides as urea equivalents in a series of histamine H2-receptor antagonists.
Lumma WC Jr, Anderson PS, Baldwin JJ, Bolhofer WA, Habecker CN, Hirshfield JM, Pietruszkiewicz AM, Randall WC, Torchiana ML, Britcher SF, Clineschmidt BV, Denny GH, Hirschmann R, Hoffman MJ, Phillips BT, Streeter KB. Lumma WC Jr, et al. Among authors: phillips bt. J Med Chem. 1982 Mar;25(3):207-10. doi: 10.1021/jm00345a002. J Med Chem. 1982. PMID: 6121913 No abstract available.
Author Correction: A joint international consensus statement for measuring quality of survival for patients with childhood cancer.
van Kalsbeek RJ, Hudson MM, Mulder RL, Ehrhardt M, Green DM, Mulrooney DA, Hakkert J, den Hartogh J, Nijenhuis A, van Santen HM, Schouten-van Meeteren AYN, van Tinteren H, Verbruggen LC, Conklin HM, Jacola LM, Webster RT, Partanen M, Kollen WJW, Grootenhuis MA, Pieters R, Kremer LCM; International Childhood Cancer Outcome Project participants. van Kalsbeek RJ, et al. Nat Med. 2024 May 22. doi: 10.1038/s41591-024-03065-9. Online ahead of print. Nat Med. 2024. PMID: 38778213 No abstract available.
Lineage-specific splicing regulation of MAPT gene in the primate brain.
Recinos Y, Bao S, Wang X, Phillips BL, Yeh YT, Weyn-Vanhentenryck SM, Swanson MS, Zhang C. Recinos Y, et al. Among authors: phillips bl. Cell Genom. 2024 May 13:100563. doi: 10.1016/j.xgen.2024.100563. Online ahead of print. Cell Genom. 2024. PMID: 38772368 Free article.
2,322 results