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Discovery of N-{(1S,2S)-2-(3-cyanophenyl)- 3-[4-(2-[18F]fluoroethoxy)phenyl]-1-methylpropyl}- 2-methyl-2-[(5-methylpyridin-2-yl)oxy]propanamide, a cannabinoid-1 receptor positron emission tomography tracer suitable for clinical use.
J Med Chem. 2007 Jul 26;50(15):3427-30. doi: 10.1021/jm070131b. Epub 2007 Jul 3.
J Med Chem. 2007.
PMID: 17608398
A novel crystallization-induced diastereomeric transformation based on a reversible carbon-sulfur bond formation. Application to the synthesis of a gamma-secretase inhibitor.
Davies AJ, Scott JP, Bishop BC, Brands KM, Brewer SE, Dasilva JO, Dormer PG, Dolling UH, Gibb AD, Hammond DC, Lieberman DR, Palucki M, Payack JF.
Davies AJ, et al. Among authors: payack jf.
J Org Chem. 2007 Jun 22;72(13):4864-71. doi: 10.1021/jo0705925. Epub 2007 May 24.
J Org Chem. 2007.
PMID: 17521199
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A non-cryogenic method for the preparation of 2-(indolyl) borates, silanes, and silanols.
Vazquez E, Davies IW, Payack JF.
Vazquez E, et al. Among authors: payack jf.
J Org Chem. 2002 Oct 18;67(21):7551-2. doi: 10.1021/jo026087j.
J Org Chem. 2002.
PMID: 12375996
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Efficient synthesis of NK(1) receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation.
Brands KM, Payack JF, Rosen JD, Nelson TD, Candelario A, Huffman MA, Zhao MM, Li J, Craig B, Song ZJ, Tschaen DM, Hansen K, Devine PN, Pye PJ, Rossen K, Dormer PG, Reamer RA, Welch CJ, Mathre DJ, Tsou NN, McNamara JM, Reider PJ.
Brands KM, et al. Among authors: payack jf.
J Am Chem Soc. 2003 Feb 26;125(8):2129-35. doi: 10.1021/ja027458g.
J Am Chem Soc. 2003.
PMID: 12590540
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A concise synthesis of a novel antiangiogenic tyrosine kinase inhibitor.
Payack JF, Vazquez E, Matty L, Kress MH, McNamara J.
Payack JF, et al.
J Org Chem. 2005 Jan 7;70(1):175-8. doi: 10.1021/jo048334k.
J Org Chem. 2005.
PMID: 15624920
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Synthesis of a potent hNK-1 receptor antagonist via an SN2 reaction of an enantiomerically pure alpha-alkoxy sulfonate.
Nelson TD, Rosen JD, Smitrovich JH, Payack J, Craig B, Matty L, Huffman MA, McNamara J.
Nelson TD, et al.
Org Lett. 2005 Jan 6;7(1):55-8. doi: 10.1021/ol047925u.
Org Lett. 2005.
PMID: 15624976
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Preclinical anticonvulsant and neuroprotective profile of 8319, a non-competitive NMDA antagonist.
Fielding S, Wilker JC, Chernack J, Ramirez V, Wilmot CA, Martin LL, Payack JF, Cornfeldt ML, Rudolphi KA, Rush DK.
Fielding S, et al. Among authors: payack jf.
Prog Clin Biol Res. 1990;361:533-41.
Prog Clin Biol Res. 1990.
PMID: 2290851
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Preclinical anxiolytic profiles of 7189 and 8319, novel non-competitive NMDA antagonists.
Dunn RW, Corbett R, Martin LL, Payack JF, Laws-Ricker L, Wilmot CA, Rush DK, Cornfeldt ML, Fielding S.
Dunn RW, et al. Among authors: payack jf.
Prog Clin Biol Res. 1990;361:495-512.
Prog Clin Biol Res. 1990.
PMID: 1981268
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