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Identification of protective Lassa virus epitopes that are restricted by HLA-A2.
Botten J, Alexander J, Pasquetto V, Sidney J, Barrowman P, Ting J, Peters B, Southwood S, Stewart B, Rodriguez-Carreno MP, Mothe B, Whitton JL, Sette A, Buchmeier MJ. Botten J, et al. J Virol. 2006 Sep;80(17):8351-61. doi: 10.1128/JVI.00896-06. J Virol. 2006. PMID: 16912286 Free PMC article.
Broad repertoire of the CD4+ Th cell response in spontaneously controlled hepatitis C virus infection includes dominant and highly promiscuous epitopes.
Schulze zur Wiesch J, Lauer GM, Day CL, Kim AY, Ouchi K, Duncan JE, Wurcel AG, Timm J, Jones AM, Mothe B, Allen TM, McGovern B, Lewis-Ximenez L, Sidney J, Sette A, Chung RT, Walker BD. Schulze zur Wiesch J, et al. J Immunol. 2005 Sep 15;175(6):3603-13. doi: 10.4049/jimmunol.175.6.3603. J Immunol. 2005. PMID: 16148104
Identification of seventeen new simian immunodeficiency virus-derived CD8+ T cell epitopes restricted by the high frequency molecule, Mamu-A*02, and potential escape from CTL recognition.
Loffredo JT, Sidney J, Wojewoda C, Dodds E, Reynolds MR, Napoé G, Mothé BR, O'Connor DH, Wilson NA, Watkins DI, Sette A. Loffredo JT, et al. Among authors: mothe br. J Immunol. 2004 Oct 15;173(8):5064-76. doi: 10.4049/jimmunol.173.8.5064. J Immunol. 2004. PMID: 15470050
The TB-specific CD4(+) T cell immune repertoire in both cynomolgus and rhesus macaques largely overlap with humans.
Mothé BR, Lindestam Arlehamn CS, Dow C, Dillon MBC, Wiseman RW, Bohn P, Karl J, Golden NA, Gilpin T, Foreman TW, Rodgers MA, Mehra S, Scriba TJ, Flynn JL, Kaushal D, O'Connor DH, Sette A. Mothé BR, et al. Tuberculosis (Edinb). 2015 Dec;95(6):722-735. doi: 10.1016/j.tube.2015.07.005. Epub 2015 Aug 28. Tuberculosis (Edinb). 2015. PMID: 26526557 Free PMC article.
Rationally engineered therapeutic proteins with reduced immunogenicity.
Tangri S, Mothé BR, Eisenbraun J, Sidney J, Southwood S, Briggs K, Zinckgraf J, Bilsel P, Newman M, Chesnut R, Licalsi C, Sette A. Tangri S, et al. Among authors: mothe br. J Immunol. 2005 Mar 15;174(6):3187-96. doi: 10.4049/jimmunol.174.6.3187. J Immunol. 2005. PMID: 15749848
40 results