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Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.
Liu X, Holstege H, van der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, van Vliet MH, Wessels LF, Peterse JL, Berns A, Jonkers J. Liu X, et al. Among authors: kerkhoven rm. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12111-6. doi: 10.1073/pnas.0702969104. Epub 2007 Jul 11. Proc Natl Acad Sci U S A. 2007. PMID: 17626182 Free PMC article.
A large-scale RNAi screen in human cells identifies new components of the p53 pathway.
Berns K, Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, Heimerikx M, Kerkhoven RM, Madiredjo M, Nijkamp W, Weigelt B, Agami R, Ge W, Cavet G, Linsley PS, Beijersbergen RL, Bernards R. Berns K, et al. Among authors: kerkhoven rm. Nature. 2004 Mar 25;428(6981):431-7. doi: 10.1038/nature02371. Nature. 2004. PMID: 15042092
Gene expression profiling in follicular lymphoma to assess clinical aggressiveness and to guide the choice of treatment.
Glas AM, Kersten MJ, Delahaye LJ, Witteveen AT, Kibbelaar RE, Velds A, Wessels LF, Joosten P, Kerkhoven RM, Bernards R, van Krieken JH, Kluin PM, van't Veer LJ, de Jong D. Glas AM, et al. Among authors: kerkhoven rm. Blood. 2005 Jan 1;105(1):301-7. doi: 10.1182/blood-2004-06-2298. Epub 2004 Sep 2. Blood. 2005. PMID: 15345589 Free article.
Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.
Brummelkamp TR, Berns K, Hijmans EM, Mullenders J, Fabius A, Heimerikx M, Velds A, Kerkhoven RM, Madiredjo M, Bernards R, Beijersbergen RL. Brummelkamp TR, et al. Among authors: kerkhoven rm. Cold Spring Harb Symp Quant Biol. 2004;69:439-45. doi: 10.1101/sqb.2004.69.439. Cold Spring Harb Symp Quant Biol. 2004. PMID: 16117679 No abstract available.
Oncogenic pathways impinging on the G2-restriction point.
Foijer F, Simonis M, van Vliet M, Wessels L, Kerkhoven R, Sorger PK, Te Riele H. Foijer F, et al. Oncogene. 2008 Feb 14;27(8):1142-54. doi: 10.1038/sj.onc.1210724. Epub 2007 Aug 13. Oncogene. 2008. PMID: 17700522
Dissecting T cell lineage relationships by cellular barcoding.
Schepers K, Swart E, van Heijst JW, Gerlach C, Castrucci M, Sie D, Heimerikx M, Velds A, Kerkhoven RM, Arens R, Schumacher TN. Schepers K, et al. Among authors: kerkhoven rm. J Exp Med. 2008 Sep 29;205(10):2309-18. doi: 10.1084/jem.20072462. Epub 2008 Sep 22. J Exp Med. 2008. PMID: 18809713 Free PMC article.
73 results