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Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype.
Genes Dev. 2007 Jul 15;21(14):1731-46. doi: 10.1101/gad.1556607. Epub 2007 Jul 12.
Genes Dev. 2007.
PMID: 17626791
Free PMC article.
p27Kip1 modulates cell migration through the regulation of RhoA activation.
Besson A, Gurian-West M, Schmidt A, Hall A, Roberts JM.
Besson A, et al. Among authors: gurian west m.
Genes Dev. 2004 Apr 15;18(8):862-76. doi: 10.1101/gad.1185504. Epub 2004 Apr 12.
Genes Dev. 2004.
PMID: 15078817
Free PMC article.
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A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression.
Besson A, Gurian-West M, Chen X, Kelly-Spratt KS, Kemp CJ, Roberts JM.
Besson A, et al. Among authors: gurian west m.
Genes Dev. 2006 Jan 1;20(1):47-64. doi: 10.1101/gad.1384406.
Genes Dev. 2006.
PMID: 16391232
Free PMC article.
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Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.
Singer JD, Gurian-West M, Clurman B, Roberts JM.
Singer JD, et al. Among authors: gurian west m.
Genes Dev. 1999 Sep 15;13(18):2375-87. doi: 10.1101/gad.13.18.2375.
Genes Dev. 1999.
PMID: 10500095
Free PMC article.
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Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication.
Zhao H, Chen X, Gurian-West M, Roberts JM.
Zhao H, et al. Among authors: gurian west m.
Mol Cell Biol. 2012 Apr;32(8):1421-32. doi: 10.1128/MCB.06721-11. Epub 2012 Feb 13.
Mol Cell Biol. 2012.
PMID: 22331465
Free PMC article.
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Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro.
Serres MP, Zlotek-Zlotkiewicz E, Concha C, Gurian-West M, Daburon V, Roberts JM, Besson A.
Serres MP, et al. Among authors: gurian west m.
Oncogene. 2011 Jun 23;30(25):2846-58. doi: 10.1038/onc.2011.9. Epub 2011 Feb 14.
Oncogene. 2011.
PMID: 21317921
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