Roberts JM - Search Results

1

Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype.

Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, Clurman BE, Dyer MA, Roberts JM. Besson A, et al. Among authors: roberts jm. Genes Dev. 2007 Jul 15;21(14):1731-46. doi: 10.1101/gad.1556607. Epub 2007 Jul 12. Genes Dev. 2007. PMID: 17626791 Free PMC article.

2

A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression.

Besson A, Gurian-West M, Chen X, Kelly-Spratt KS, Kemp CJ, Roberts JM. Besson A, et al. Among authors: roberts jm. Genes Dev. 2006 Jan 1;20(1):47-64. doi: 10.1101/gad.1384406. Genes Dev. 2006. PMID: 16391232 Free PMC article.

3

A mechanism misregulating p27 in tumors discovered in a functional genomic screen.

Garrett-Engele CM, Tasch MA, Hwang HC, Fero ML, Perlmutter RM, Clurman BE, Roberts JM. Garrett-Engele CM, et al. Among authors: roberts jm. PLoS Genet. 2007 Dec;3(12):e219. doi: 10.1371/journal.pgen.0030219. PLoS Genet. 2007. PMID: 18069898 Free PMC article.

4

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

Minella AC, Loeb KR, Knecht A, Welcker M, Varnum-Finney BJ, Bernstein ID, Roberts JM, Clurman BE. Minella AC, et al. Among authors: roberts jm. Genes Dev. 2008 Jun 15;22(12):1677-89. doi: 10.1101/gad.1650208. Genes Dev. 2008. PMID: 18559482 Free PMC article.

5

p27Kip1 modulates cell migration through the regulation of RhoA activation.

Besson A, Gurian-West M, Schmidt A, Hall A, Roberts JM. Besson A, et al. Among authors: roberts jm. Genes Dev. 2004 Apr 15;18(8):862-76. doi: 10.1101/gad.1185504. Epub 2004 Apr 12. Genes Dev. 2004. PMID: 15078817 Free PMC article.

6

Cyclin E-CDK2 is a regulator of p27Kip1.

Sheaff RJ, Groudine M, Gordon M, Roberts JM, Clurman BE. Sheaff RJ, et al. Among authors: roberts jm. Genes Dev. 1997 Jun 1;11(11):1464-78. doi: 10.1101/gad.11.11.1464. Genes Dev. 1997. PMID: 9192873 Free article.

7

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.

Singer JD, Gurian-West M, Clurman B, Roberts JM. Singer JD, et al. Among authors: roberts jm. Genes Dev. 1999 Sep 15;13(18):2375-87. doi: 10.1101/gad.13.18.2375. Genes Dev. 1999. PMID: 10500095 Free PMC article.

8

A mouse model for cyclin E-dependent genetic instability and tumorigenesis.

Loeb KR, Kostner H, Firpo E, Norwood T, D Tsuchiya K, Clurman BE, Roberts JM. Loeb KR, et al. Among authors: roberts jm. Cancer Cell. 2005 Jul;8(1):35-47. doi: 10.1016/j.ccr.2005.06.010. Cancer Cell. 2005. PMID: 16023597 Free article.

9

p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex.

Nguyen L, Besson A, Heng JI, Schuurmans C, Teboul L, Parras C, Philpott A, Roberts JM, Guillemot F. Nguyen L, et al. Among authors: roberts jm. Genes Dev. 2006 Jun 1;20(11):1511-24. doi: 10.1101/gad.377106. Epub 2006 May 16. Genes Dev. 2006. PMID: 16705040 Free PMC article.

10

Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome.

Chen X, Barton LF, Chi Y, Clurman BE, Roberts JM. Chen X, et al. Among authors: roberts jm. Mol Cell. 2007 Jun 22;26(6):843-52. doi: 10.1016/j.molcel.2007.05.022. Mol Cell. 2007. PMID: 17588519 Free PMC article.

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