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Presence of homozygous KIT exon 11 mutations is strongly associated with malignant clinical behavior in gastrointestinal stromal tumors.
Lasota J, vel Dobosz AJ, Wasag B, Wozniak A, Kraszewska E, Michej W, Ptaszynski K, Rutkowski P, Sarlomo-Rikala M, Steigen SE, Schneider-Stock R, Stachura J, Chosia M, Ogun G, Ruka W, Siedlecki JA, Miettinen M. Lasota J, et al. Among authors: vel dobosz aj. Lab Invest. 2007 Oct;87(10):1029-41. doi: 10.1038/labinvest.3700628. Epub 2007 Jul 16. Lab Invest. 2007. PMID: 17632543 Free article.
Predictive factors for long-term effects of imatinib therapy in patients with inoperable/metastatic CD117(+) gastrointestinal stromal tumors (GISTs).
Rutkowski P, Nowecki ZI, Debiec-Rychter M, Grzesiakowska U, Michej W, Woźniak A, Siedlecki JA, Limon J, vel Dobosz AJ, Kakol M, Osuch C, Ruka W. Rutkowski P, et al. Among authors: vel dobosz aj. J Cancer Res Clin Oncol. 2007 Sep;133(9):589-97. doi: 10.1007/s00432-007-0202-4. Epub 2007 Apr 26. J Cancer Res Clin Oncol. 2007. PMID: 17458563
Functional features of gene expression profiles differentiating gastrointestinal stromal tumours according to KIT mutations and expression.
Ostrowski J, Polkowski M, Paziewska A, Skrzypczak M, Goryca K, Rubel T, Kokoszyñska K, Rutkowski P, Nowecki ZI, Vel Dobosz AJ, Jarosz D, Ruka W, Wyrwicz LS. Ostrowski J, et al. Among authors: vel dobosz aj. BMC Cancer. 2009 Nov 27;9:413. doi: 10.1186/1471-2407-9-413. BMC Cancer. 2009. PMID: 19943934 Free PMC article.