Bourget K - Search Results

1

The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU.

Rahman MK, Umashankar B, Choucair H, Bourget K, Rawling T, Murray M. Rahman MK, et al. Among authors: bourget k. Int J Biochem Cell Biol. 2024 Jun;171:106571. doi: 10.1016/j.biocel.2024.106571. Epub 2024 Apr 11. Int J Biochem Cell Biol. 2024. PMID: 38608921 Free article.

2

Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids.

Rahman MK, Umashankar B, Choucair H, Pazderka C, Bourget K, Chen Y, Dunstan CR, Rawling T, Murray M. Rahman MK, et al. Among authors: bourget k. Eur J Pharmacol. 2023 Jan 15;939:175470. doi: 10.1016/j.ejphar.2022.175470. Epub 2022 Dec 18. Eur J Pharmacol. 2023. PMID: 36543287

3

The ixabepilone and vandetanib combination shows synergistic activity in docetaxel-resistant MDA-MB-231 breast cancer cells.

Tam S, Al-Zubaidi Y, Rahman MK, Bourget K, Zhou F, Murray M. Tam S, et al. Among authors: bourget k. Pharmacol Rep. 2022 Oct;74(5):998-1010. doi: 10.1007/s43440-022-00396-7. Epub 2022 Jul 30. Pharmacol Rep. 2022. PMID: 35908023 Free PMC article.

4

Preclinical Evaluation of Ixabepilone in Combination with VEGF Receptor and PARP Inhibitors in Taxane-Sensitive and Taxane-Resistant MDA-MB-231 Breast Cancer Cells.

Rahman MK, Al-Zubaidi Y, Bourget K, Chen Y, Tam S, Zhou F, Murray M. Rahman MK, et al. Among authors: bourget k. J Pharm Sci. 2022 Aug;111(8):2180-2190. doi: 10.1016/j.xphs.2022.06.009. Epub 2022 Jun 11. J Pharm Sci. 2022. PMID: 35700798

5

The aryl-ureido fatty acid CTU activates endoplasmic reticulum stress and PERK/NOXA-mediated apoptosis in tumor cells by a dual mitochondrial-targeting mechanism.

Choucair H, Rahman MK, Umashankar B, Al-Zubaidi Y, Bourget K, Chen Y, Dunstan C, Rawling T, Murray M. Choucair H, et al. Among authors: bourget k. Cancer Lett. 2022 Feb 1;526:131-141. doi: 10.1016/j.canlet.2021.11.022. Epub 2021 Nov 22. Cancer Lett. 2022. PMID: 34822928

6

PTU, a novel ureido-fatty acid, inhibits MDA-MB-231 cell invasion and dissemination by modulating Wnt5a secretion and cytoskeletal signaling.

Al-Zubaidi Y, Chen Y, Khalilur Rahman M, Umashankar B, Choucair H, Bourget K, Chung L, Qi Y, Witting PK, Anderson RL, O'Neill GM, Dunstan CR, Rawling T, Murray M. Al-Zubaidi Y, et al. Among authors: bourget k. Biochem Pharmacol. 2021 Oct;192:114726. doi: 10.1016/j.bcp.2021.114726. Epub 2021 Aug 10. Biochem Pharmacol. 2021. PMID: 34389322

7

Aryl urea substituted fatty acids: a new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter.

Rawling T, MacDermott-Opeskin H, Roseblade A, Pazderka C, Clarke C, Bourget K, Wu X, Lewis W, Noble B, Gale PA, O'Mara ML, Cranfield C, Murray M. Rawling T, et al. Among authors: bourget k. Chem Sci. 2020 Aug 19;11(47):12677-12685. doi: 10.1039/d0sc02777d. Chem Sci. 2020. PMID: 34094462 Free PMC article.

8

Vestibular evoked myogenic potentials.

Dorbeau C, Bourget K, Renard L, Calais C, Bakhos D. Dorbeau C, et al. Among authors: bourget k. Eur Ann Otorhinolaryngol Head Neck Dis. 2021 Dec;138(6):483-488. doi: 10.1016/j.anorl.2021.01.001. Epub 2021 Jan 19. Eur Ann Otorhinolaryngol Head Neck Dis. 2021. PMID: 33483282 Free article.

9

Herndon K, Braithwaite J, Berry B, Bourget K. Herndon K, et al. Among authors: bourget k. BioDrugs. 2021 Jan;35(1):103-112. doi: 10.1007/s40259-020-00463-6. Epub 2021 Jan 5. BioDrugs. 2021. PMID: 33400238

10

Carbon Chain Length Modulates MDA-MB-231 Breast Cancer Cell Killing Mechanisms by Mitochondrially Targeted Aryl-Urea Fatty Acids.

Murray M, Roseblade A, Chen Y, Bourget K, Rawling T. Murray M, et al. Among authors: bourget k. ChemMedChem. 2020 Jan 17;15(2):247-255. doi: 10.1002/cmdc.201900577. Epub 2020 Jan 9. ChemMedChem. 2020. PMID: 31773850

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