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Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy.
Van Mil SW, Milona A, Dixon PH, Mullenbach R, Geenes VL, Chambers J, Shevchuk V, Moore GE, Lammert F, Glantz AG, Mattsson LA, Whittaker J, Parker MG, White R, Williamson C. Van Mil SW, et al. Among authors: parker mg. Gastroenterology. 2007 Aug;133(2):507-16. doi: 10.1053/j.gastro.2007.05.015. Epub 2007 May 23. Gastroenterology. 2007. PMID: 17681172
The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.
Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, Cairns W, Schoonjans K, Milligan S, Parker M, White R, Williamson C. Milona A, et al. Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G151-8. doi: 10.1152/ajpgi.00336.2009. Epub 2009 Oct 8. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 19815629 Free PMC article.
Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotype.
Abu-Hayyeh S, Papacleovoulou G, Lövgren-Sandblom A, Tahir M, Oduwole O, Jamaludin NA, Ravat S, Nikolova V, Chambers J, Selden C, Rees M, Marschall HU, Parker MG, Williamson C. Abu-Hayyeh S, et al. Among authors: parker mg. Hepatology. 2013 Feb;57(2):716-26. doi: 10.1002/hep.26055. Epub 2013 Jan 8. Hepatology. 2013. PMID: 22961653 Free PMC article.
Metabolic regulation by the nuclear receptor corepressor RIP140.
Christian M, White R, Parker MG. Christian M, et al. Among authors: parker mg. Trends Endocrinol Metab. 2006 Aug;17(6):243-50. doi: 10.1016/j.tem.2006.06.008. Epub 2006 Jul 11. Trends Endocrinol Metab. 2006. PMID: 16815031 Review.
Nuclear receptors spring into action.
Parker MG, White R. Parker MG, et al. Nat Struct Biol. 1996 Feb;3(2):113-5. doi: 10.1038/nsb0296-113. Nat Struct Biol. 1996. PMID: 8564533 No abstract available.
381 results