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Nortriptyline delays disease onset in models of chronic neurodegeneration.
Wang H, Guan Y, Wang X, Smith K, Cormier K, Zhu S, Stavrovskaya IG, Huo C, Ferrante RJ, Kristal BS, Friedlander RM. Wang H, et al. Among authors: smith k. Eur J Neurosci. 2007 Aug;26(3):633-41. doi: 10.1111/j.1460-9568.2007.05663.x. Eur J Neurosci. 2007. PMID: 17686041
The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity.
Wang X, Sirianni A, Pei Z, Cormier K, Smith K, Jiang J, Zhou S, Wang H, Zhao R, Yano H, Kim JE, Li W, Kristal BS, Ferrante RJ, Friedlander RM. Wang X, et al. Among authors: smith k. J Neurosci. 2011 Oct 12;31(41):14496-507. doi: 10.1523/JNEUROSCI.3059-11.2011. J Neurosci. 2011. PMID: 21994366 Free PMC article.
Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis.
Zhang Y, Cook A, Kim J, Baranov SV, Jiang J, Smith K, Cormier K, Bennett E, Browser RP, Day AL, Carlisle DL, Ferrante RJ, Wang X, Friedlander RM. Zhang Y, et al. Among authors: smith k. Neurobiol Dis. 2013 Jul;55:26-35. doi: 10.1016/j.nbd.2013.03.008. Epub 2013 Mar 26. Neurobiol Dis. 2013. PMID: 23537713 Free PMC article.
Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.
Ferrante RJ, Ryu H, Kubilus JK, D'Mello S, Sugars KL, Lee J, Lu P, Smith K, Browne S, Beal MF, Kristal BS, Stavrovskaya IG, Hewett S, Rubinsztein DC, Langley B, Ratan RR. Ferrante RJ, et al. Among authors: smith k. J Neurosci. 2004 Nov 17;24(46):10335-42. doi: 10.1523/JNEUROSCI.2599-04.2004. J Neurosci. 2004. PMID: 15548647 Free PMC article.
Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.
Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ. Stack EC, et al. Among authors: smith km. J Neurosci. 2007 Nov 21;27(47):12908-15. doi: 10.1523/JNEUROSCI.4318-07.2007. J Neurosci. 2007. PMID: 18032664 Free PMC article.
Modulation of nucleosome dynamics in Huntington's disease.
Stack EC, Del Signore SJ, Luthi-Carter R, Soh BY, Goldstein DR, Matson S, Goodrich S, Markey AL, Cormier K, Hagerty SW, Smith K, Ryu H, Ferrante RJ. Stack EC, et al. Among authors: smith k. Hum Mol Genet. 2007 May 15;16(10):1164-75. doi: 10.1093/hmg/ddm064. Epub 2007 Apr 2. Hum Mol Genet. 2007. PMID: 17403718 Free article.
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