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Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts.
Browning BL, Annese V, Barclay ML, Bingham SA, Brand S, Büning C, Castro M, Cucchiara S, Dallapiccola B, Drummond H, Ferguson LR, Ferraris A, Fisher SA, Gearry RB, Glas J, Henckaerts L, Huebner C, Knafelz D, Lakatos L, Lakatos PL, Latiano A, Liu X, Mathew C, Müller-Myhsok B, Newman WG, Nimmo ER, Noble CL, Palmieri O, Parkes M, Petermann I, Rutgeerts P, Satsangi J, Shelling AN, Siminovitch KA, Török HP, Tremelling M, Vermeire S, Valvano MR, Witt H. Browning BL, et al. Among authors: witt h. J Med Genet. 2008 Jan;45(1):36-42. doi: 10.1136/jmg.2007.050773. Epub 2007 Aug 10. J Med Genet. 2008. PMID: 17693570
DLG5 variants in inflammatory bowel disease.
Büning C, Geerdts L, Fiedler T, Gentz E, Pitre G, Reuter W, Luck W, Buhner S, Molnar T, Nagy F, Lonovics J, Dignass A, Landt O, Nickel R, Genschel J, Lochs H, Schmidt HH, Witt H. Büning C, et al. Among authors: witt h. Am J Gastroenterol. 2006 Apr;101(4):786-92. doi: 10.1111/j.1572-0241.2006.00431.x. Epub 2006 Feb 22. Am J Gastroenterol. 2006. PMID: 16494592
No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts.
Büning C, Schmidt HH, Molnár T, Drenth JP, Fiedler T, Gentz E, Todorov T, Baumgart DC, Sturm A, Nagy F, Lonovics J, de Jong DJ, Landt O, Kage A, Nickel R, Büttner J, Lochs H, Witt H. Büning C, et al. Among authors: witt h. Inflamm Bowel Dis. 2008 Mar;14(3):332-7. doi: 10.1002/ibd.20337. Inflamm Bowel Dis. 2008. PMID: 18092344
Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.
Büning C, Schmidt HH, Molnar T, De Jong DJ, Fiedler T, Bühner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Drenth JP, Landt O, Nickel R, Büttner J, Lochs H, Witt H. Büning C, et al. Among authors: witt h. Aliment Pharmacol Ther. 2007 Oct 1;26(7):1025-33. doi: 10.1111/j.1365-2036.2007.03446.x. Aliment Pharmacol Ther. 2007. PMID: 17877509 Free article.
Polymorphisms of UDP-glucuronosyltransferase 1A7 are not involved in pancreatic diseases.
Verlaan M, Drenth JP, Truninger K, Koudova M, Schulz HU, Bargetzi M, Künzli B, Friess H, Cerny M, Kage A, Landt O, te Morsche RH, Rosendahl J, Luck W, Nickel R, Halangk J, Becker M, Macek M Jr, Jansen JB, Witt H. Verlaan M, et al. Among authors: witt h. J Med Genet. 2005 Oct;42(10):e62. doi: 10.1136/jmg.2005.032599. J Med Genet. 2005. PMID: 16199544 Free PMC article.
HFE genotypes in patients with chronic pancreatitis and pancreatic adenocarcinoma.
Hucl T, Kylanpää-Bäck ML, Witt H, Künzli B, Lempinen M, Schneider A, Kemppainen E, Löhr M, Friess H, Ockenga J, Rosendahl J, Schulz HU, Gress T, Singer MV, Pfützer RH. Hucl T, et al. Among authors: witt h. Genet Med. 2007 Jul;9(7):479-83. doi: 10.1097/gim.0b013e3180986df4. Genet Med. 2007. PMID: 17666895 Free article. Clinical Trial.
The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease.
Baumgart DC, Buning C, Geerdts L, Schmidt HH, Genschel J, Fiedler T, Gentz E, Molnar T, Nagy F, Lonovics J, Lochs H, Wiedenmann B, Nickel R, Witt H, Dignass A. Baumgart DC, et al. Among authors: witt h. Digestion. 2007;76(3-4):196-202. doi: 10.1159/000112646. Epub 2007 Dec 21. Digestion. 2007. PMID: 18174680
A study in three European IBD cohorts confirms that the ATG16L1 c.898A>G (p.Thr300Ala) variant is a susceptibility factor for Crohn's disease.
Büning C, Durmus T, Molnar T, de Jong DJ, Drenth JP, Fiedler T, Gentz E, Todorov T, Haas V, Buhner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Landt O, Kage A, Büning H, Nickel R, Büttner J, Lochs H, Schmidt HH, Witt H. Büning C, et al. Among authors: witt h. J Crohns Colitis. 2007 Dec;1(2):70-6. doi: 10.1016/j.crohns.2007.08.001. Epub 2007 Sep 27. J Crohns Colitis. 2007. PMID: 21172187
472 results