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Elucidation of the substrate specificity of the MASP-2 protease of the lectin complement pathway and identification of the enzyme as a major physiological target of the serpin, C1-inhibitor.
Kerr FK, Thomas AR, Wijeyewickrema LC, Whisstock JC, Boyd SE, Kaiserman D, Matthews AY, Bird PI, Thielens NM, Rossi V, Pike RN. Kerr FK, et al. Among authors: pike rn. Mol Immunol. 2008 Feb;45(3):670-7. doi: 10.1016/j.molimm.2007.07.008. Epub 2007 Aug 20. Mol Immunol. 2008. PMID: 17709141
Serpins in the Caenorhabditis elegans genome.
Whisstock JC, Irving JA, Bottomley SP, Pike RN, Lesk AM. Whisstock JC, et al. Among authors: pike rn. Proteins. 1999 Jul 1;36(1):31-41. doi: 10.1002/(sici)1097-0134(19990701)36:1<31::aid-prot3>3.3.co;2-h. Proteins. 1999. PMID: 10373004
Cleaved antitrypsin polymers at atomic resolution.
Dunstone MA, Dai W, Whisstock JC, Rossjohn J, Pike RN, Feil SC, Le Bonniec BF, Parker MW, Bottomley SP. Dunstone MA, et al. Among authors: pike rn. Protein Sci. 2000 Feb;9(2):417-20. doi: 10.1110/ps.9.2.417. Protein Sci. 2000. PMID: 10716194 Free PMC article.
Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation.
Irving JA, Shushanov SS, Pike RN, Popova EY, Brömme D, Coetzer TH, Bottomley SP, Boulynko IA, Grigoryev SA, Whisstock JC. Irving JA, et al. Among authors: pike rn. J Biol Chem. 2002 Apr 12;277(15):13192-201. doi: 10.1074/jbc.M108460200. Epub 2002 Jan 30. J Biol Chem. 2002. PMID: 11821386 Free article.
165 results