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RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.
J Mol Biol. 2007 Oct 12;373(1):38-47. doi: 10.1016/j.jmb.2007.07.068. Epub 2007 Aug 15.
J Mol Biol. 2007.
PMID: 17765923
Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.
Gottipati P, Vischioni B, Schultz N, Solomons J, Bryant HE, Djureinovic T, Issaeva N, Sleeth K, Sharma RA, Helleday T.
Gottipati P, et al.
Cancer Res. 2010 Jul 1;70(13):5389-98. doi: 10.1158/0008-5472.CAN-09-4716. Epub 2010 Jun 15.
Cancer Res. 2010.
PMID: 20551068
Free article.
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6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance.
Issaeva N, Thomas HD, Djureinovic T, Jaspers JE, Stoimenov I, Kyle S, Pedley N, Gottipati P, Zur R, Sleeth K, Chatzakos V, Mulligan EA, Lundin C, Gubanova E, Kersbergen A, Harris AL, Sharma RA, Rottenberg S, Curtin NJ, Helleday T.
Issaeva N, et al.
Cancer Res. 2010 Aug 1;70(15):6268-76. doi: 10.1158/0008-5472.CAN-09-3416. Epub 2010 Jul 14.
Cancer Res. 2010.
PMID: 20631063
Free PMC article.
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Repair of abasic sites in DNA.
Dianov GL, Sleeth KM, Dianova II, Allinson SL.
Dianov GL, et al. Among authors: sleeth km.
Mutat Res. 2003 Oct 29;531(1-2):157-63. doi: 10.1016/j.mrfmmm.2003.09.003.
Mutat Res. 2003.
PMID: 14637252
Review.
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Imaging DNA damage in vivo using gammaH2AX-targeted immunoconjugates.
Cornelissen B, Kersemans V, Darbar S, Thompson J, Shah K, Sleeth K, Hill MA, Vallis KA.
Cornelissen B, et al.
Cancer Res. 2011 Jul 1;71(13):4539-49. doi: 10.1158/0008-5472.CAN-10-4587. Epub 2011 May 17.
Cancer Res. 2011.
PMID: 21586614
Free PMC article.
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Orchestration of base excision repair by controlling the rates of enzymatic activities.
Allinson SL, Sleeth KM, Matthewman GE, Dianov GL.
Allinson SL, et al. Among authors: sleeth km.
DNA Repair (Amst). 2004 Jan 5;3(1):23-31. doi: 10.1016/j.dnarep.2003.09.002.
DNA Repair (Amst). 2004.
PMID: 14697756
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XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
Dianova II, Sleeth KM, Allinson SL, Parsons JL, Breslin C, Caldecott KW, Dianov GL.
Dianova II, et al. Among authors: sleeth km.
Nucleic Acids Res. 2004 May 11;32(8):2550-5. doi: 10.1093/nar/gkh567. Print 2004.
Nucleic Acids Res. 2004.
PMID: 15141024
Free PMC article.
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Exchangeability of mammalian DNA ligases between base excision repair pathways.
Sleeth KM, Robson RL, Dianov GL.
Sleeth KM, et al.
Biochemistry. 2004 Oct 12;43(40):12924-30. doi: 10.1021/bi0492612.
Biochemistry. 2004.
PMID: 15461465
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