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Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.
Podust LM, von Kries JP, Eddine AN, Kim Y, Yermalitskaya LV, Kuehne R, Ouellet H, Warrier T, Alteköster M, Lee JS, Rademann J, Oschkinat H, Kaufmann SH, Waterman MR. Podust LM, et al. Among authors: rademann j. Antimicrob Agents Chemother. 2007 Nov;51(11):3915-23. doi: 10.1128/AAC.00311-07. Epub 2007 Sep 10. Antimicrob Agents Chemother. 2007. PMID: 17846131 Free PMC article.
Combinatorial Chemistry in the Commercial Jungle.
Rademann J. Rademann J. Angew Chem Int Ed Engl. 2001 Jul 16;40(14):2721. doi: 10.1002/1521-3773(20010716)40:14<2721::aid-anie2721>3.0.co;2-2. Angew Chem Int Ed Engl. 2001. PMID: 11458385 No abstract available.
Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity.
Chakrabarti A, Witsenburg JJ, Sinzinger MD, Richter M, Wallbrecher R, Cluitmans JC, Verdurmen WP, Tanis S, Adjobo-Hermans MJ, Rademann J, Brock R. Chakrabarti A, et al. Among authors: rademann j. Biochim Biophys Acta. 2014 Dec;1838(12):3097-106. doi: 10.1016/j.bbamem.2014.08.001. Epub 2014 Aug 7. Biochim Biophys Acta. 2014. PMID: 25109936 Free article.
136 results