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Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival.
Yang H, Yang T, Baur JA, Perez E, Matsui T, Carmona JJ, Lamming DW, Souza-Pinto NC, Bohr VA, Rosenzweig A, de Cabo R, Sauve AA, Sinclair DA. Yang H, et al. Among authors: lamming dw. Cell. 2007 Sep 21;130(6):1095-107. doi: 10.1016/j.cell.2007.07.035. Cell. 2007. PMID: 17889652 Free PMC article.
Targeting the biology of aging with mTOR inhibitors.
Mannick JB, Lamming DW. Mannick JB, et al. Among authors: lamming dw. Nat Aging. 2023 Jun;3(6):642-660. doi: 10.1038/s43587-023-00416-y. Epub 2023 May 4. Nat Aging. 2023. PMID: 37142830 Free PMC article. Review.
Blazing a trail for the clinical use of rapamycin as a geroprotecTOR.
Konopka AR, Lamming DW; RAP PAC Investigators; EVERLAST Investigators. Konopka AR, et al. Among authors: lamming dw. Geroscience. 2023 Oct;45(5):2769-2783. doi: 10.1007/s11357-023-00935-x. Epub 2023 Oct 6. Geroscience. 2023. PMID: 37801202 Free PMC article.
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. Howitz KT, et al. Among authors: lamming dw. Nature. 2003 Sep 11;425(6954):191-6. doi: 10.1038/nature01960. Epub 2003 Aug 24. Nature. 2003. PMID: 12939617
110 results