Freeman GJ - Search Results

1

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction.

Kaufmann DE, Kavanagh DG, Pereyra F, Zaunders JJ, Mackey EW, Miura T, Palmer S, Brockman M, Rathod A, Piechocka-Trocha A, Baker B, Zhu B, Le Gall S, Waring MT, Ahern R, Moss K, Kelleher AD, Coffin JM, Freeman GJ, Rosenberg ES, Walker BD. Kaufmann DE, et al. Among authors: freeman gj. Nat Immunol. 2007 Nov;8(11):1246-54. doi: 10.1038/ni1515. Epub 2007 Sep 30. Nat Immunol. 2007. PMID: 17906628

2

CTLA-4 and CD28 mRNA are coexpressed in most T cells after activation. Expression of CTLA-4 and CD28 mRNA does not correlate with the pattern of lymphokine production.

Freeman GJ, Lombard DB, Gimmi CD, Brod SA, Lee K, Laning JC, Hafler DA, Dorf ME, Gray GS, Reiser H, et al. Freeman GJ, et al. J Immunol. 1992 Dec 15;149(12):3795-801. J Immunol. 1992. PMID: 1281186

3

Expression of a hypoglycosylated form of CD86 (B7-2) on human T cells with altered binding properties to CD28 and CTLA-4.

Höllsberg P, Scholz C, Anderson DE, Greenfield EA, Kuchroo VK, Freeman GJ, Hafler DA. Höllsberg P, et al. Among authors: freeman gj. J Immunol. 1997 Nov 15;159(10):4799-805. J Immunol. 1997. PMID: 9366404

4

PD-L2 is a second ligand for PD-1 and inhibits T cell activation.

Latchman Y, Wood CR, Chernova T, Chaudhary D, Borde M, Chernova I, Iwai Y, Long AJ, Brown JA, Nunes R, Greenfield EA, Bourque K, Boussiotis VA, Carter LL, Carreno BM, Malenkovich N, Nishimura H, Okazaki T, Honjo T, Sharpe AH, Freeman GJ. Latchman Y, et al. Among authors: freeman gj. Nat Immunol. 2001 Mar;2(3):261-8. doi: 10.1038/85330. Nat Immunol. 2001. PMID: 11224527

5

ICOS is critical for CD40-mediated antibody class switching.

McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, Freeman GJ, Sharpe AH. McAdam AJ, et al. Among authors: freeman gj. Nature. 2001 Jan 4;409(6816):102-5. doi: 10.1038/35051107. Nature. 2001. PMID: 11343122

6

CD4+CD25high regulatory cells in human peripheral blood.

Baecher-Allan C, Brown JA, Freeman GJ, Hafler DA. Baecher-Allan C, et al. Among authors: freeman gj. J Immunol. 2001 Aug 1;167(3):1245-53. doi: 10.4049/jimmunol.167.3.1245. J Immunol. 2001. PMID: 11466340

7

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells.

Tzachanis D, Freeman GJ, Hirano N, van Puijenbroek AA, Delfs MW, Berezovskaya A, Nadler LM, Boussiotis VA. Tzachanis D, et al. Among authors: freeman gj. Nat Immunol. 2001 Dec;2(12):1174-82. doi: 10.1038/ni730. Nat Immunol. 2001. PMID: 11694881

8

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.

Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Monney L, et al. Among authors: freeman gj. Nature. 2002 Jan 31;415(6871):536-41. doi: 10.1038/415536a. Nature. 2002. PMID: 11823861

9

The B7-CD28 superfamily.

Sharpe AH, Freeman GJ. Sharpe AH, et al. Among authors: freeman gj. Nat Rev Immunol. 2002 Feb;2(2):116-26. doi: 10.1038/nri727. Nat Rev Immunol. 2002. PMID: 11910893 Review.

10

Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production.

Brown JA, Dorfman DM, Ma FR, Sullivan EL, Munoz O, Wood CR, Greenfield EA, Freeman GJ. Brown JA, et al. Among authors: freeman gj. J Immunol. 2003 Feb 1;170(3):1257-66. doi: 10.4049/jimmunol.170.3.1257. J Immunol. 2003. PMID: 12538684

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