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Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes.
Diabetes. 2008 Jan;57(1):199-208. doi: 10.2337/db07-0830. Epub 2007 Oct 16.
Diabetes. 2008.
PMID: 17940120
Free PMC article.
Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.
Green-Mitchell SM, Tersey SA, Cole BK, Ma K, Kuhn NS, Cunningham TD, Maybee NA, Chakrabarti SK, McDuffie M, Taylor-Fishwick DA, Mirmira RG, Nadler JL, Morris MA.
Green-Mitchell SM, et al. Among authors: maybee na.
PLoS One. 2013;8(2):e56763. doi: 10.1371/journal.pone.0056763. Epub 2013 Feb 21.
PLoS One. 2013.
PMID: 23437231
Free PMC article.
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Is anti-inflammatory therapy for type 2 diabetes mellitus ready for routine clinical practice?
Maybee NA, Worrall BB, Nadler JL.
Maybee NA, et al.
Nat Clin Pract Endocrinol Metab. 2007 Dec;3(12):806-7. doi: 10.1038/ncpendmet0645. Epub 2007 Sep 18.
Nat Clin Pract Endocrinol Metab. 2007.
PMID: 17876346
Free PMC article.
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