Alhamadsheh MM - Search Results

1

Total synthesis and selective activity of a new class of conformationally restrained epothilones.

Alhamadsheh MM, Gupta S, Hudson RA, Perera L, Tillekeratne LM. Alhamadsheh MM, et al. Chemistry. 2008;14(2):570-81. doi: 10.1002/chem.200701143. Chemistry. 2008. PMID: 17955508 Free PMC article.

2

Design, total synthesis, and evaluation of novel open-chain epothilone analogues.

Alhamadsheh MM, Hudson RA, Viranga Tillekeratne LM. Alhamadsheh MM, et al. Org Lett. 2006 Feb 16;8(4):685-8. doi: 10.1021/ol0528787. Org Lett. 2006. PMID: 16468742

3

Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes.

Alhamadsheh MM, Musayev F, Komissarov AA, Sachdeva S, Wright HT, Scarsdale N, Florova G, Reynolds KA. Alhamadsheh MM, et al. Chem Biol. 2007 May;14(5):513-24. doi: 10.1016/j.chembiol.2007.03.013. Chem Biol. 2007. PMID: 17524982

4

Antimalarial activity of natural and synthetic prodiginines.

Papireddy K, Smilkstein M, Kelly JX, Shweta, Salem SM, Alhamadsheh M, Haynes SW, Challis GL, Reynolds KA. Papireddy K, et al. J Med Chem. 2011 Aug 11;54(15):5296-306. doi: 10.1021/jm200543y. Epub 2011 Jul 8. J Med Chem. 2011. PMID: 21736388 Free PMC article.

5

AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin.

Penchala SC, Connelly S, Wang Y, Park MS, Zhao L, Baranczak A, Rappley I, Vogel H, Liedtke M, Witteles RM, Powers ET, Reixach N, Chan WK, Wilson IA, Kelly JW, Graef IA, Alhamadsheh MM. Penchala SC, et al. Among authors: alhamadsheh mm. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9992-7. doi: 10.1073/pnas.1300761110. Epub 2013 May 28. Proc Natl Acad Sci U S A. 2013. PMID: 23716704 Free PMC article.

6

Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis.

Turos E, Revell KD, Ramaraju P, Gergeres DA, Greenhalgh K, Young A, Sathyanarayan N, Dickey S, Lim D, Alhamadsheh MM, Reynolds K. Turos E, et al. Among authors: alhamadsheh mm. Bioorg Med Chem. 2008 Jul 1;16(13):6501-8. doi: 10.1016/j.bmc.2008.05.032. Epub 2008 May 17. Bioorg Med Chem. 2008. PMID: 18524602 Free PMC article.

7

Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors.

Alhamadsheh MM, Waters NC, Sachdeva S, Lee P, Reynolds KA. Alhamadsheh MM, et al. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6402-5. doi: 10.1016/j.bmcl.2008.10.097. Epub 2008 Oct 25. Bioorg Med Chem Lett. 2008. PMID: 18996691

8

Enhancing the Safety and Efficacy of PSMA-Based Small-Molecule Drug Conjugates by Linker Stabilization and Conjugation to Transthyretin Binding Ligand.

Amin TU, Emara R, Pal A, Aldawod H, Jiang G, Liang D, Haque Tuhin MT, Balgoname A, Patel AD, Alhamadsheh MM. Amin TU, et al. Among authors: alhamadsheh mm. J Med Chem. 2022 Nov 24;65(22):15473-15486. doi: 10.1021/acs.jmedchem.2c01423. Epub 2022 Nov 3. J Med Chem. 2022. PMID: 36327103

9

Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH).

Alhamadsheh MM, Waters NC, Huddler DP, Kreishman-Deitrick M, Florova G, Reynolds KA. Alhamadsheh MM, et al. Bioorg Med Chem Lett. 2007 Feb 15;17(4):879-83. doi: 10.1016/j.bmcl.2006.11.067. Epub 2006 Dec 1. Bioorg Med Chem Lett. 2007. PMID: 17189694

10

Modular polyketide synthases and cis double bond formation: establishment of activated cis-3-cyclohexylpropenoic acid as the diketide intermediate in phoslactomycin biosynthesis.

Alhamadsheh MM, Palaniappan N, Daschouduri S, Reynolds KA. Alhamadsheh MM, et al. J Am Chem Soc. 2007 Feb 21;129(7):1910-1. doi: 10.1021/ja068818t. Epub 2007 Jan 27. J Am Chem Soc. 2007. PMID: 17256943 Free PMC article.

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