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High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project.
Kato N, Miyata T, Tabara Y, Katsuya T, Yanai K, Hanada H, Kamide K, Nakura J, Kohara K, Takeuchi F, Mano H, Yasunami M, Kimura A, Kita Y, Ueshima H, Nakayama T, Soma M, Hata A, Fujioka A, Kawano Y, Nakao K, Sekine A, Yoshida T, Nakamura Y, Saruta T, Ogihara T, Sugano S, Miki T, Tomoike H. Kato N, et al. Among authors: kohara k. Hum Mol Genet. 2008 Feb 15;17(4):617-27. doi: 10.1093/hmg/ddm335. Epub 2007 Nov 14. Hum Mol Genet. 2008. PMID: 18003638
Accumulation of common polymorphisms is associated with development of hypertension: a 12-year follow-up from the Ohasama study.
Watanabe Y, Metoki H, Ohkubo T, Katsuya T, Tabara Y, Kikuya M, Hirose T, Sugimoto K, Asayama K, Inoue R, Hara A, Obara T, Nakura J, Kohara K, Totsune K, Ogihara T, Rakugi H, Miki T, Imai Y. Watanabe Y, et al. Among authors: kohara k. Hypertens Res. 2010 Feb;33(2):129-34. doi: 10.1038/hr.2009.193. Epub 2009 Nov 20. Hypertens Res. 2010. PMID: 19927152
The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMA-IR in Japanese population.
Onuma H, Tabara Y, Kawamoto R, Shimizu I, Kawamura R, Takata Y, Nishida W, Ohashi J, Miki T, Kohara K, Makino H, Osawa H. Onuma H, et al. Among authors: kohara k. J Hum Genet. 2010 Sep;55(9):600-4. doi: 10.1038/jhg.2010.75. Epub 2010 Jun 24. J Hum Genet. 2010. PMID: 20574426
Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project.
Tabara Y, Kohara K, Kita Y, Hirawa N, Katsuya T, Ohkubo T, Hiura Y, Tajima A, Morisaki T, Miyata T, Nakayama T, Takashima N, Nakura J, Kawamoto R, Takahashi N, Hata A, Soma M, Imai Y, Kokubo Y, Okamura T, Tomoike H, Iwai N, Ogihara T, Inoue I, Tokunaga K, Johnson T, Caulfield M, Munroe P; Global Blood Pressure Genetics Consortium; Umemura S, Ueshima H, Miki T. Tabara Y, et al. Among authors: kohara k. Hypertension. 2010 Nov;56(5):973-80. doi: 10.1161/HYPERTENSIONAHA.110.153429. Epub 2010 Oct 4. Hypertension. 2010. PMID: 20921432 Free PMC article.
439 results