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Therapy of ovarian cancers with targeted cytotoxic analogs of bombesin, somatostatin, and luteinizing hormone-releasing hormone and their combinations.
Buchholz S, Keller G, Schally AV, Halmos G, Hohla F, Heinrich E, Koester F, Baker B, Engel JB. Buchholz S, et al. Among authors: hohla f. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10403-10407. doi: 10.1073/pnas.0602971103. Epub 2006 Jun 26. Proc Natl Acad Sci U S A. 2006. PMID: 16801542 Free PMC article.
Antagonists of growth hormone-releasing hormone inhibit growth of androgen-independent prostate cancer through inactivation of ERK and Akt kinases.
Rick FG, Schally AV, Szalontay L, Block NL, Szepeshazi K, Nadji M, Zarandi M, Hohla F, Buchholz S, Seitz S. Rick FG, et al. Among authors: hohla f. Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1655-60. doi: 10.1073/pnas.1120588109. Epub 2012 Jan 18. Proc Natl Acad Sci U S A. 2012. PMID: 22307626 Free PMC article.
Triple-negative breast cancers express receptors for luteinizing hormone-releasing hormone (LHRH) and respond to LHRH antagonist cetrorelix with growth inhibition.
Buchholz S, Seitz S, Schally AV, Engel JB, Rick FG, Szalontay L, Hohla F, Krishan A, Papadia A, Gaiser T, Brockhoff G, Ortmann O, Diedrich K, Köster F. Buchholz S, et al. Among authors: hohla f. Int J Oncol. 2009 Oct;35(4):789-96. doi: 10.3892/ijo_00000391. Int J Oncol. 2009. PMID: 19724914
38 results