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122 results

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Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.
Biggadike K, Boudjelal M, Clackers M, Coe DM, Demaine DA, Hardy GW, Humphreys D, Inglis GG, Johnston MJ, Jones HT, House D, Loiseau R, Needham D, Skone PA, Uings I, Veitch G, Weingarten GG, McLay IM, Macdonald SJ. Biggadike K, et al. Among authors: johnston mj. J Med Chem. 2007 Dec 27;50(26):6519-34. doi: 10.1021/jm070778w. Epub 2007 Nov 27. J Med Chem. 2007. PMID: 18038970
Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series.
Barker M, Clackers M, Copley R, Demaine DA, Humphreys D, Inglis GG, Johnston MJ, Jones HT, Haase MV, House D, Loiseau R, Nisbet L, Pacquet F, Skone PA, Shanahan SE, Tape D, Vinader VM, Washington M, Uings I, Upton R, McLay IM, Macdonald SJ. Barker M, et al. Among authors: johnston mj. J Med Chem. 2006 Jul 13;49(14):4216-31. doi: 10.1021/jm060302x. J Med Chem. 2006. PMID: 16821781
Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimetics.
Clackers M, Coe DM, Demaine DA, Hardy GW, Humphreys D, Inglis GG, Johnston MJ, Jones HT, House D, Loiseau R, Minick DJ, Skone PA, Uings I, McLay IM, Macdonald SJ. Clackers M, et al. Among authors: johnston mj. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4737-45. doi: 10.1016/j.bmcl.2007.06.066. Epub 2007 Jun 26. Bioorg Med Chem Lett. 2007. PMID: 17616395
H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs.
Krug B, Hu B, Chen H, Ptack A, Chen X, Gretarsson KH, Deshmukh S, Kabir N, Andrade AF, Jabbour E, Harutyunyan AS, Lee JJY, Hulswit M, Faury D, Russo C, Xu X, Johnston MJ, Baguette A, Dahl NA, Weil AG, Ellezam B, Dali R, Blanchette M, Wilson K, Garcia BA, Soni RK, Gallo M, Taylor MD, Kleinman CL, Majewski J, Jabado N, Lu C. Krug B, et al. Among authors: johnston mj. bioRxiv [Preprint]. 2023 Nov 28:2023.11.28.567931. doi: 10.1101/2023.11.28.567931. bioRxiv. 2023. PMID: 38116029 Free PMC article. Preprint.
Strategies for the production of isotopically labelled Fab fragments of therapeutic antibodies in Komagataella phaffii (Pichia pastoris) and Escherichia coli for NMR studies.
Gagné D, Sarker M, Gingras G, Hodgson DJ, Frahm G, Creskey M, Lorbetskie B, Bigelow S, Wang J, Zhang X, Johnston MJW, Lu H, Aubin Y. Gagné D, et al. Among authors: johnston mjw. PLoS One. 2023 Nov 29;18(11):e0294406. doi: 10.1371/journal.pone.0294406. eCollection 2023. PLoS One. 2023. PMID: 38019850 Free PMC article.
Linked-read based analysis of the medulloblastoma genome.
Zwaig M, Johnston MJ, Lee JJY, Farooq H, Gallo M, Jabado N, Taylor MD, Ragoussis J. Zwaig M, et al. Among authors: johnston mj. Front Oncol. 2023 Jul 28;13:1221611. doi: 10.3389/fonc.2023.1221611. eCollection 2023. Front Oncol. 2023. PMID: 37576901 Free PMC article.
Preferred definitive surgical management of Crohn's perianal fistulas and factors influencing surgical decision making in Australia and New Zealand.
De Gregorio M, Sidhu A, Behrenbruch C, Connor SJ, Guerra G, Johnston MJ, Keck JO, Ong EJSK, Thompson AJ, Woods R, D'Souza B, Ding NS. De Gregorio M, et al. Among authors: johnston mj. ANZ J Surg. 2024 Feb;94(1-2):14-16. doi: 10.1111/ans.18640. Epub 2023 Aug 8. ANZ J Surg. 2024. PMID: 37551939 No abstract available.
122 results