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Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.
Biggadike K, Boudjelal M, Clackers M, Coe DM, Demaine DA, Hardy GW, Humphreys D, Inglis GG, Johnston MJ, Jones HT, House D, Loiseau R, Needham D, Skone PA, Uings I, Veitch G, Weingarten GG, McLay IM, Macdonald SJ. Biggadike K, et al. Among authors: veitch g. J Med Chem. 2007 Dec 27;50(26):6519-34. doi: 10.1021/jm070778w. Epub 2007 Nov 27. J Med Chem. 2007. PMID: 18038970
The synthesis of azadirachtin: a potent insect antifeedant.
Ley SV, Abad-Somovilla A, Anderson JC, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca MG, Brice A, Broughton HB, Burke BJ, Cleator E, Craig D, Denholm AA, Denton RM, Durand-Reville T, Gobbi LB, Göbel M, Gray BL, Grossmann RB, Gutteridge CE, Hahn N, Harding SL, Jennens DC, Jennens L, Lovell PJ, Lovell HJ, de la Puente ML, Kolb HC, Koot WJ, Maslen SL, McCusker CF, Mattes A, Pape AR, Pinto A, Santafianos D, Scott JS, Smith SC, Somers AQ, Spilling CD, Stelzer F, Toogood PL, Turner RM, Veitch GE, Wood A, Zumbrunn C. Ley SV, et al. Among authors: veitch ge. Chemistry. 2008;14(34):10683-704. doi: 10.1002/chem.200801103. Chemistry. 2008. PMID: 18821532
A relay route for the synthesis of azadirachtin.
Veitch GE, Beckmann E, Burke BJ, Boyer A, Ayats C, Ley SV. Veitch GE, et al. Angew Chem Int Ed Engl. 2007;46(40):7633-5. doi: 10.1002/anie.200703028. Angew Chem Int Ed Engl. 2007. PMID: 17665383 No abstract available.
Synthesis of azadirachtin: a long but successful journey.
Veitch GE, Beckmann E, Burke BJ, Boyer A, Maslen SL, Ley SV. Veitch GE, et al. Angew Chem Int Ed Engl. 2007;46(40):7629-32. doi: 10.1002/anie.200703027. Angew Chem Int Ed Engl. 2007. PMID: 17665403 No abstract available.
The azadirachtin story.
Veitch GE, Boyer A, Ley SV. Veitch GE, et al. Angew Chem Int Ed Engl. 2008;47(49):9402-29. doi: 10.1002/anie.200802675. Angew Chem Int Ed Engl. 2008. PMID: 19031481 Review.
37 results