Birnbaum MJ - Search Results

1

Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease.

Fernández-Hernando C, Ackah E, Yu J, Suárez Y, Murata T, Iwakiri Y, Prendergast J, Miao RQ, Birnbaum MJ, Sessa WC. Fernández-Hernando C, et al. Among authors: birnbaum mj. Cell Metab. 2007 Dec;6(6):446-57. doi: 10.1016/j.cmet.2007.10.007. Cell Metab. 2007. PMID: 18054314 Free PMC article.

2

Akt1/protein kinase Balpha is critical for ischemic and VEGF-mediated angiogenesis.

Ackah E, Yu J, Zoellner S, Iwakiri Y, Skurk C, Shibata R, Ouchi N, Easton RM, Galasso G, Birnbaum MJ, Walsh K, Sessa WC. Ackah E, et al. Among authors: birnbaum mj. J Clin Invest. 2005 Aug;115(8):2119-27. doi: 10.1172/JCI24726. J Clin Invest. 2005. PMID: 16075056 Free PMC article.

3

Akt-mediated foxo1 inhibition is required for liver regeneration.

Pauta M, Rotllan N, Fernández-Hernando A, Langhi C, Ribera J, Lu M, Boix L, Bruix J, Jimenez W, Suárez Y, Ford DA, Baldán A, Birnbaum MJ, Morales-Ruiz M, Fernández-Hernando C. Pauta M, et al. Among authors: birnbaum mj. Hepatology. 2016 May;63(5):1660-74. doi: 10.1002/hep.28286. Epub 2015 Dec 18. Hepatology. 2016. PMID: 26473496 Free PMC article.

4

Phosphorylation of GATA-6 is required for vascular smooth muscle cell differentiation after mTORC1 inhibition.

Xie Y, Jin Y, Merenick BL, Ding M, Fetalvero KM, Wagner RJ, Mai A, Gleim S, Tucker DF, Birnbaum MJ, Ballif BA, Luciano AK, Sessa WC, Rzucidlo EM, Powell RJ, Hou L, Zhao H, Hwa J, Yu J, Martin KA. Xie Y, et al. Among authors: birnbaum mj. Sci Signal. 2015 May 12;8(376):ra44. doi: 10.1126/scisignal.2005482. Sci Signal. 2015. PMID: 25969542 Free PMC article.

5

Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation.

Boxer RB, Stairs DB, Dugan KD, Notarfrancesco KL, Portocarrero CP, Keister BA, Belka GK, Cho H, Rathmell JC, Thompson CB, Birnbaum MJ, Chodosh LA. Boxer RB, et al. Among authors: birnbaum mj. Cell Metab. 2006 Dec;4(6):475-90. doi: 10.1016/j.cmet.2006.10.011. Cell Metab. 2006. PMID: 17141631 Free article.

6

A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

O'Neill BT, Kim J, Wende AR, Theobald HA, Tuinei J, Buchanan J, Guo A, Zaha VG, Davis DK, Schell JC, Boudina S, Wayment B, Litwin SE, Shioi T, Izumo S, Birnbaum MJ, Abel ED. O'Neill BT, et al. Among authors: birnbaum mj. Cell Metab. 2007 Oct;6(4):294-306. doi: 10.1016/j.cmet.2007.09.001. Cell Metab. 2007. PMID: 17908558 Free PMC article.

7

A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition.

Wan M, Leavens KF, Hunter RW, Koren S, von Wilamowitz-Moellendorff A, Lu M, Satapati S, Chu Q, Sakamoto K, Burgess SC, Birnbaum MJ. Wan M, et al. Among authors: birnbaum mj. Cell Metab. 2013 Jul 2;18(1):99-105. doi: 10.1016/j.cmet.2013.06.001. Cell Metab. 2013. PMID: 23823480 Free PMC article.

8

Akt1 deficiency in schizophrenia and impairment of hippocampal plasticity and function.

Balu DT, Carlson GC, Talbot K, Kazi H, Hill-Smith TE, Easton RM, Birnbaum MJ, Lucki I. Balu DT, et al. Among authors: birnbaum mj. Hippocampus. 2012 Feb;22(2):230-40. doi: 10.1002/hipo.20887. Epub 2010 Nov 3. Hippocampus. 2012. PMID: 21049487 Free PMC article.

9

Postprandial hepatic lipid metabolism requires signaling through Akt2 independent of the transcription factors FoxA2, FoxO1, and SREBP1c.

Wan M, Leavens KF, Saleh D, Easton RM, Guertin DA, Peterson TR, Kaestner KH, Sabatini DM, Birnbaum MJ. Wan M, et al. Among authors: birnbaum mj. Cell Metab. 2011 Oct 5;14(4):516-27. doi: 10.1016/j.cmet.2011.09.001. Cell Metab. 2011. PMID: 21982711 Free PMC article.

10

Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes.

Perry RJ, Camporez JG, Kursawe R, Titchenell PM, Zhang D, Perry CJ, Jurczak MJ, Abudukadier A, Han MS, Zhang XM, Ruan HB, Yang X, Caprio S, Kaech SM, Sul HS, Birnbaum MJ, Davis RJ, Cline GW, Petersen KF, Shulman GI. Perry RJ, et al. Among authors: birnbaum mj. Cell. 2015 Feb 12;160(4):745-758. doi: 10.1016/j.cell.2015.01.012. Epub 2015 Feb 5. Cell. 2015. PMID: 25662011 Free PMC article.

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