Ludwig T - Search Results

1

Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, Memeo L, Ludwig T, Ethier SP, Krogh M, Szabolcs M, Murty VV, Isola J, Hibshoosh H, Parsons R, Borg A. Saal LH, et al. Among authors: ludwig t. Nat Genet. 2008 Jan;40(1):102-7. doi: 10.1038/ng.2007.39. Epub 2007 Dec 9. Nat Genet. 2008. PMID: 18066063 Free PMC article.

2

Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.

Laufer M, Nandula SV, Modi AP, Wang S, Jasin M, Murty VV, Ludwig T, Baer R. Laufer M, et al. Among authors: ludwig t. J Biol Chem. 2007 Nov 23;282(47):34325-33. doi: 10.1074/jbc.M705198200. Epub 2007 Sep 11. J Biol Chem. 2007. PMID: 17848578 Free article.

3

The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression.

Reczek CR, Szabolcs M, Stark JM, Ludwig T, Baer R. Reczek CR, et al. Among authors: ludwig t. J Cell Biol. 2013 May 27;201(5):693-707. doi: 10.1083/jcb.201302145. J Cell Biol. 2013. PMID: 23712259 Free PMC article.

4

The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression.

Shakya R, Szabolcs M, McCarthy E, Ospina E, Basso K, Nandula S, Murty V, Baer R, Ludwig T. Shakya R, et al. Among authors: ludwig t. Proc Natl Acad Sci U S A. 2008 May 13;105(19):7040-5. doi: 10.1073/pnas.0711032105. Epub 2008 Apr 28. Proc Natl Acad Sci U S A. 2008. PMID: 18443292 Free PMC article.

5

The DNA resection protein CtIP promotes mammary tumorigenesis.

Reczek CR, Shakya R, Miteva Y, Szabolcs M, Ludwig T, Baer R. Reczek CR, et al. Among authors: ludwig t. Oncotarget. 2016 May 31;7(22):32172-83. doi: 10.18632/oncotarget.8605. Oncotarget. 2016. PMID: 27058754 Free PMC article.

6

Development of mammary adenocarcinomas by tissue-specific knockout of Brca2 in mice.

Ludwig T, Fisher P, Murty V, Efstratiadis A. Ludwig T, et al. Oncogene. 2001 Jul 5;20(30):3937-48. doi: 10.1038/sj.onc.1204512. Oncogene. 2001. PMID: 11494122

7

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.

Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T. Shakya R, et al. Among authors: ludwig t. Science. 2011 Oct 28;334(6055):525-8. doi: 10.1126/science.1209909. Science. 2011. PMID: 22034435 Free PMC article.

8

Murine models for familial pancreatic cancer: Histopathology, latency and drug sensitivity among cancers of Palb2, Brca1 and Brca2 mutant mouse strains.

Park D, Shakya R, Koivisto C, Pitarresi JR, Szabolcs M, Kladney R, Hadjis A, Mace TA, Ludwig T. Park D, et al. Among authors: ludwig t. PLoS One. 2019 Dec 26;14(12):e0226714. doi: 10.1371/journal.pone.0226714. eCollection 2019. PLoS One. 2019. PMID: 31877165 Free PMC article.

9

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis.

Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Chen Z, et al. Among authors: ludwig t. Nature. 2005 Aug 4;436(7051):725-30. doi: 10.1038/nature03918. Nature. 2005. PMID: 16079851 Free PMC article.

10

'Designer' tumors in mice.

Politi K, Kljuic A, Szabolcs M, Fisher P, Ludwig T, Efstratiadis A. Politi K, et al. Among authors: ludwig t. Oncogene. 2004 Feb 26;23(8):1558-65. doi: 10.1038/sj.onc.1207275. Oncogene. 2004. PMID: 14661057

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