Orkin SH - Search Results

1

ETV6-NTRK3 fusion oncogene initiates breast cancer from committed mammary progenitors via activation of AP1 complex.

Li Z, Tognon CE, Godinho FJ, Yasaitis L, Hock H, Herschkowitz JI, Lannon CL, Cho E, Kim SJ, Bronson RT, Perou CM, Sorensen PH, Orkin SH. Li Z, et al. Among authors: orkin sh. Cancer Cell. 2007 Dec;12(6):542-58. doi: 10.1016/j.ccr.2007.11.012. Cancer Cell. 2007. PMID: 18068631 Free PMC article.

2

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages.

Porcher C, Swat W, Rockwell K, Fujiwara Y, Alt FW, Orkin SH. Porcher C, et al. Among authors: orkin sh. Cell. 1996 Jul 12;86(1):47-57. doi: 10.1016/s0092-8674(00)80076-8. Cell. 1996. PMID: 8689686 Free article.

3

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.

Gao Y, Sun Y, Frank KM, Dikkes P, Fujiwara Y, Seidl KJ, Sekiguchi JM, Rathbun GA, Swat W, Wang J, Bronson RT, Malynn BA, Bryans M, Zhu C, Chaudhuri J, Davidson L, Ferrini R, Stamato T, Orkin SH, Greenberg ME, Alt FW. Gao Y, et al. Among authors: orkin sh. Cell. 1998 Dec 23;95(7):891-902. doi: 10.1016/s0092-8674(00)81714-6. Cell. 1998. PMID: 9875844 Free article.

4

Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5.

Roberts CW, Leroux MM, Fleming MD, Orkin SH. Roberts CW, et al. Among authors: orkin sh. Cancer Cell. 2002 Nov;2(5):415-25. doi: 10.1016/s1535-6108(02)00185-x. Cancer Cell. 2002. PMID: 12450796 Free article.

5

Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation.

Hock H, Hamblen MJ, Rooke HM, Traver D, Bronson RT, Cameron S, Orkin SH. Hock H, et al. Among authors: orkin sh. Immunity. 2003 Jan;18(1):109-20. doi: 10.1016/s1074-7613(02)00501-0. Immunity. 2003. PMID: 12530980 Free article.

6

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene.

Mikkola HK, Klintman J, Yang H, Hock H, Schlaeger TM, Fujiwara Y, Orkin SH. Mikkola HK, et al. Among authors: orkin sh. Nature. 2003 Jan 30;421(6922):547-51. doi: 10.1038/nature01345. Epub 2003 Jan 19. Nature. 2003. PMID: 12540851

7

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression.

Neumann CA, Krause DS, Carman CV, Das S, Dubey DP, Abraham JL, Bronson RT, Fujiwara Y, Orkin SH, Van Etten RA. Neumann CA, et al. Among authors: orkin sh. Nature. 2003 Jul 31;424(6948):561-5. doi: 10.1038/nature01819. Nature. 2003. PMID: 12891360 Free article.

8

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

Tuveson DA, Shaw AT, Willis NA, Silver DP, Jackson EL, Chang S, Mercer KL, Grochow R, Hock H, Crowley D, Hingorani SR, Zaks T, King C, Jacobetz MA, Wang L, Bronson RT, Orkin SH, DePinho RA, Jacks T. Tuveson DA, et al. Among authors: orkin sh. Cancer Cell. 2004 Apr;5(4):375-87. doi: 10.1016/s1535-6108(04)00085-6. Cancer Cell. 2004. PMID: 15093544 Free article.

9

Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival.

Hock H, Meade E, Medeiros S, Schindler JW, Valk PJ, Fujiwara Y, Orkin SH. Hock H, et al. Among authors: orkin sh. Genes Dev. 2004 Oct 1;18(19):2336-41. doi: 10.1101/gad.1239604. Epub 2004 Sep 15. Genes Dev. 2004. PMID: 15371326 Free PMC article.

10

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells.

Hock H, Hamblen MJ, Rooke HM, Schindler JW, Saleque S, Fujiwara Y, Orkin SH. Hock H, et al. Among authors: orkin sh. Nature. 2004 Oct 21;431(7011):1002-7. doi: 10.1038/nature02994. Epub 2004 Sep 29. Nature. 2004. PMID: 15457180 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

652 results

Search Page