Yu S - Search Results

1

Pharmacodynamic markers of perifosine efficacy.

Hennessy BT, Lu Y, Poradosu E, Yu Q, Yu S, Hall H, Carey MS, Ravoori M, Gonzalez-Angulo AM, Birch R, Henderson IC, Kundra V, Mills GB. Hennessy BT, et al. Among authors: yu q, yu s. Clin Cancer Res. 2007 Dec 15;13(24):7421-31. doi: 10.1158/1078-0432.CCR-07-0760. Clin Cancer Res. 2007. PMID: 18094426

2

Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.

Fang X, Yu S, Tanyi JL, Lu Y, Woodgett JR, Mills GB. Fang X, et al. Among authors: yu s. Mol Cell Biol. 2002 Apr;22(7):2099-110. doi: 10.1128/MCB.22.7.2099-2110.2002. Mol Cell Biol. 2002. PMID: 11884598 Free PMC article.

3

Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages.

Visentin B, Vekich JA, Sibbald BJ, Cavalli AL, Moreno KM, Matteo RG, Garland WA, Lu Y, Yu S, Hall HS, Kundra V, Mills GB, Sabbadini RA. Visentin B, et al. Among authors: yu s. Cancer Cell. 2006 Mar;9(3):225-38. doi: 10.1016/j.ccr.2006.02.023. Cancer Cell. 2006. PMID: 16530706 Free article.

4

Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells.

Yu S, Murph MM, Lu Y, Liu S, Hall HS, Liu J, Stephens C, Fang X, Mills GB. Yu S, et al. J Natl Cancer Inst. 2008 Nov 19;100(22):1630-42. doi: 10.1093/jnci/djn378. Epub 2008 Nov 11. J Natl Cancer Inst. 2008. PMID: 19001604 Free PMC article.

5

High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability.

Cheung LW, Hennessy BT, Li J, Yu S, Myers AP, Djordjevic B, Lu Y, Stemke-Hale K, Dyer MD, Zhang F, Ju Z, Cantley LC, Scherer SE, Liang H, Lu KH, Broaddus RR, Mills GB. Cheung LW, et al. Among authors: yu s. Cancer Discov. 2011 Jul;1(2):170-85. doi: 10.1158/2159-8290.CD-11-0039. Epub 2011 Jun 7. Cancer Discov. 2011. PMID: 21984976 Free PMC article.

6

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

Cheung LW, Yu S, Zhang D, Li J, Ng PK, Panupinthu N, Mitra S, Ju Z, Yu Q, Liang H, Hawke DH, Lu Y, Broaddus RR, Mills GB. Cheung LW, et al. Among authors: yu q, yu s. Cancer Cell. 2014 Oct 13;26(4):479-94. doi: 10.1016/j.ccell.2014.08.017. Epub 2014 Oct 2. Cancer Cell. 2014. PMID: 25284480 Free PMC article.

7

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A.

Fang X, Yu SX, Lu Y, Bast RC Jr, Woodgett JR, Mills GB. Fang X, et al. Among authors: yu sx. Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):11960-5. doi: 10.1073/pnas.220413597. Proc Natl Acad Sci U S A. 2000. PMID: 11035810 Free PMC article.

8

Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cells.

Hasegawa Y, Murph M, Yu S, Tigyi G, Mills GB. Hasegawa Y, et al. Among authors: yu s. Mol Oncol. 2008 Jun;2(1):54-69. doi: 10.1016/j.molonc.2008.03.009. Mol Oncol. 2008. PMID: 19081821 Free PMC article.

9

Lysophosphatidic acid-induced transcriptional profile represents serous epithelial ovarian carcinoma and worsened prognosis.

Murph MM, Liu W, Yu S, Lu Y, Hall H, Hennessy BT, Lahad J, Schaner M, Helland A, Kristensen G, Børresen-Dale AL, Mills GB. Murph MM, et al. Among authors: yu s. PLoS One. 2009;4(5):e5583. doi: 10.1371/journal.pone.0005583. Epub 2009 May 15. PLoS One. 2009. PMID: 19440550 Free PMC article.

10

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.

Liang H, Cheung LW, Li J, Ju Z, Yu S, Stemke-Hale K, Dogruluk T, Lu Y, Liu X, Gu C, Guo W, Scherer SE, Carter H, Westin SN, Dyer MD, Verhaak RG, Zhang F, Karchin R, Liu CG, Lu KH, Broaddus RR, Scott KL, Hennessy BT, Mills GB. Liang H, et al. Among authors: yu s. Genome Res. 2012 Nov;22(11):2120-9. doi: 10.1101/gr.137596.112. Epub 2012 Oct 1. Genome Res. 2012. PMID: 23028188 Free PMC article.

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