Sorokin EP - Search Results

1

Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I.

Cheng B, Sorokin EP, Tse-Dinh YC. Cheng B, et al. Among authors: sorokin ep. Nucleic Acids Res. 2008 Feb;36(3):1017-25. doi: 10.1093/nar/gkm1126. Epub 2007 Dec 20. Nucleic Acids Res. 2008. PMID: 18096618 Free PMC article.

2

Asp-to-Asn substitution at the first position of the DxD TOPRIM motif of recombinant bacterial topoisomerase I is extremely lethal to E. coli.

Cheng B, Annamalai T, Sorokin E, Abrenica M, Aedo S, Tse-Dinh YC. Cheng B, et al. J Mol Biol. 2009 Jan 16;385(2):558-67. doi: 10.1016/j.jmb.2008.10.073. Epub 2008 Nov 5. J Mol Biol. 2009. PMID: 19013470 Free PMC article.

3

The strictly conserved Arg-321 residue in the active site of Escherichia coli topoisomerase I plays a critical role in DNA rejoining.

Narula G, Annamalai T, Aedo S, Cheng B, Sorokin E, Wong A, Tse-Dinh YC. Narula G, et al. J Biol Chem. 2011 May 27;286(21):18673-80. doi: 10.1074/jbc.M111.229450. Epub 2011 Apr 7. J Biol Chem. 2011. PMID: 21478161 Free PMC article.

4

Inhibition of Mg2+ binding and DNA religation by bacterial topoisomerase I via introduction of an additional positive charge into the active site region.

Sorokin EP, Cheng B, Rathi S, Aedo SJ, Abrenica MV, Tse-Dinh YC. Sorokin EP, et al. Nucleic Acids Res. 2008 Aug;36(14):4788-96. doi: 10.1093/nar/gkn460. Epub 2008 Jul 24. Nucleic Acids Res. 2008. PMID: 18653534 Free PMC article.

5

Genetic Evidence for Distinct Biological Mechanisms That Link Adiposity to Type 2 Diabetes: Toward Precision Medicine.

Abraham A, Cule M, Thanaj M, Basty N, Hashemloo MA, Sorokin EP, Whitcher B, Burgess S, Bell JD, Sattar N, Thomas EL, Yaghootkar H. Abraham A, et al. Among authors: sorokin ep. Diabetes. 2024 Jun 1;73(6):1012-1025. doi: 10.2337/db23-1005. Diabetes. 2024. PMID: 38530928 Free PMC article.

6

Precision MRI phenotyping of muscle volume and quality at a population scale.

Thanaj M, Basty N, Whitcher B, Sorokin EP, Liu Y, Srinivasan R, Cule M, Thomas EL, Bell JD. Thanaj M, et al. Among authors: sorokin ep. Front Physiol. 2024 Feb 2;15:1288657. doi: 10.3389/fphys.2024.1288657. eCollection 2024. Front Physiol. 2024. PMID: 38370011 Free PMC article.

7

Liver shape analysis using statistical parametric maps at population scale.

Thanaj M, Basty N, Cule M, Sorokin EP, Whitcher B, Bell JD, Thomas EL. Thanaj M, et al. Among authors: sorokin ep. BMC Med Imaging. 2024 Jan 9;24(1):15. doi: 10.1186/s12880-023-01149-5. BMC Med Imaging. 2024. PMID: 38195400 Free PMC article.

8

Kidney shape statistical analysis: associations with disease and anthropometric factors.

Thanaj M, Basty N, Cule M, Sorokin EP, Whitcher B, Srinivasan R, Lennon R, Bell JD, Thomas EL. Thanaj M, et al. Among authors: sorokin ep. BMC Nephrol. 2023 Dec 6;24(1):362. doi: 10.1186/s12882-023-03407-8. BMC Nephrol. 2023. PMID: 38057740 Free PMC article.

9

Admixture mapping of peripheral artery disease in a Dominican population reveals a putative risk locus on 2q35.

Cullina S, Wojcik GL, Shemirani R, Klarin D, Gorman BR, Sorokin EP, Gignoux CR, Belbin GM, Pyarajan S, Asgari S, Tsao PS, Damrauer SM, Abul-Husn NS, Kenny EE. Cullina S, et al. Among authors: sorokin ep. Front Genet. 2023 Aug 1;14:1181167. doi: 10.3389/fgene.2023.1181167. eCollection 2023. Front Genet. 2023. PMID: 37600667 Free PMC article.

10

Abdominal imaging associates body composition with COVID-19 severity.

Basty N, Sorokin EP, Thanaj M, Srinivasan R, Whitcher B, Bell JD, Cule M, Thomas EL. Basty N, et al. Among authors: sorokin ep. PLoS One. 2023 Apr 13;18(4):e0283506. doi: 10.1371/journal.pone.0283506. eCollection 2023. PLoS One. 2023. PMID: 37053189 Free PMC article.

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