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Exploiting the PI3K/AKT pathway for cancer drug discovery.
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Hennessy BT, et al. Among authors: mills gb. Nat Rev Drug Discov. 2005 Dec;4(12):988-1004. doi: 10.1038/nrd1902. Nat Rev Drug Discov. 2005. PMID: 16341064 Review.
Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling.
Lu Y, Muller M, Smith D, Dutta B, Komurov K, Iadevaia S, Ruths D, Tseng JT, Yu S, Yu Q, Nakhleh L, Balazsi G, Donnelly J, Schurdak M, Morgan-Lappe S, Fesik S, Ram PT, Mills GB. Lu Y, et al. Among authors: mills gb. Oncogene. 2011 Nov 10;30(45):4567-77. doi: 10.1038/onc.2011.164. Epub 2011 Jun 13. Oncogene. 2011. PMID: 21666717 Free PMC article.
Bioinformatics and systems biology.
Ram PT, Mendelsohn J, Mills GB. Ram PT, et al. Among authors: mills gb. Mol Oncol. 2012 Apr;6(2):147-54. doi: 10.1016/j.molonc.2012.01.008. Epub 2012 Feb 17. Mol Oncol. 2012. PMID: 22377422 Free PMC article. Review.
Cancer Systems Biology: a peek into the future of patient care?
Werner HM, Mills GB, Ram PT. Werner HM, et al. Among authors: mills gb. Nat Rev Clin Oncol. 2014 Mar;11(3):167-76. doi: 10.1038/nrclinonc.2014.6. Epub 2014 Feb 4. Nat Rev Clin Oncol. 2014. PMID: 24492837 Free PMC article. Review.
A pan-cancer proteomic perspective on The Cancer Genome Atlas.
Akbani R, Ng PK, Werner HM, Shahmoradgoli M, Zhang F, Ju Z, Liu W, Yang JY, Yoshihara K, Li J, Ling S, Seviour EG, Ram PT, Minna JD, Diao L, Tong P, Heymach JV, Hill SM, Dondelinger F, Städler N, Byers LA, Meric-Bernstam F, Weinstein JN, Broom BM, Verhaak RG, Liang H, Mukherjee S, Lu Y, Mills GB. Akbani R, et al. Among authors: mills gb. Nat Commun. 2014 May 29;5:3887. doi: 10.1038/ncomms4887. Nat Commun. 2014. PMID: 24871328 Free PMC article.
Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1α and oxidative phosphorylation in melanoma.
Gopal YN, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, Scolyer RA, Pupo G, Komurov K, Sehgal V, Zhang J, Patel L, Pereira CG, Broom BM, Mills GB, Ram P, Smith PD, Wargo JA, Long GV, Davies MA. Gopal YN, et al. Among authors: mills gb. Cancer Res. 2014 Dec 1;74(23):7037-47. doi: 10.1158/0008-5472.CAN-14-1392. Epub 2014 Oct 8. Cancer Res. 2014. PMID: 25297634 Free PMC article.
Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks.
Chiu HS, Llobet-Navas D, Yang X, Chung WJ, Ambesi-Impiombato A, Iyer A, Kim HR, Seviour EG, Luo Z, Sehgal V, Moss T, Lu Y, Ram P, Silva J, Mills GB, Califano A, Sumazin P. Chiu HS, et al. Among authors: mills gb. Genome Res. 2015 Feb;25(2):257-67. doi: 10.1101/gr.178194.114. Epub 2014 Nov 5. Genome Res. 2015. PMID: 25378249 Free PMC article.
1,137 results