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Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.
Liedén A, Winge MC, Sääf A, Kockum I, Ekelund E, Rodriguez E, Fölster-Holst R, Franke A, Illig T, Tengvall-Linder M, Baurecht H, Weidinger S, Wahlgren CF, Nordenskjöld M, Bradley M. Liedén A, et al. Among authors: ekelund e. PLoS One. 2012;7(11):e49694. doi: 10.1371/journal.pone.0049694. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189155 Free PMC article.
Cornulin, a marker of late epidermal differentiation, is down-regulated in eczema.
Liedén A, Ekelund E, Kuo IC, Kockum I, Huang CH, Mallbris L, Lee SP, Seng LK, Chin GY, Wahlgren CF, Palmer CN, Björkstén B, Ståhle M, Nordenskjöld M, Bradley M, Chua KY, D'Amato M. Liedén A, et al. Among authors: ekelund e. Allergy. 2009 Feb;64(2):304-11. doi: 10.1111/j.1398-9995.2008.01856.x. Epub 2008 Dec 24. Allergy. 2009. PMID: 19133922
Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis.
Ekelund E, Saaf A, Tengvall-Linder M, Melen E, Link J, Barker J, Reynolds NJ, Meggitt SJ, Kere J, Wahlgren CF, Pershagen G, Wickman M, Nordenskjold M, Kockum I, Bradley M. Ekelund E, et al. Am J Hum Genet. 2006 Jun;78(6):1060-5. doi: 10.1086/504272. Epub 2006 Apr 14. Am J Hum Genet. 2006. PMID: 16685656 Free PMC article.
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