Sackett DL - Search Results

1

Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel.

Sissung TM, Danesi R, Price DK, Steinberg SM, de Wit R, Zahid M, Gaikwad N, Cavalieri E, Dahut WL, Sackett DL, Figg WD, Sparreboom A. Sissung TM, et al. Among authors: sackett dl. Mol Cancer Ther. 2008 Jan;7(1):19-26. doi: 10.1158/1535-7163.MCT-07-0557. Epub 2008 Jan 9. Mol Cancer Ther. 2008. PMID: 18187806

2

Clinical outcome in children with recurrent neuroblastoma treated with ABT-751 and effect of ABT-751 on proliferation of neuroblastoma cell lines and on tubulin polymerization in vitro.

Meany HJ, Sackett DL, Maris JM, Ward Y, Krivoshik A, Cohn SL, Steinberg SM, Balis FM, Fox E. Meany HJ, et al. Among authors: sackett dl. Pediatr Blood Cancer. 2010 Jan;54(1):47-54. doi: 10.1002/pbc.22267. Pediatr Blood Cancer. 2010. PMID: 19731320 Free PMC article. Clinical Trial.

3

Rigosertib Induces Mitotic Arrest and Apoptosis in RAS-Mutated Rhabdomyosarcoma and Neuroblastoma.

Kowalczyk JT, Wan X, Hernandez ER, Luo R, Lyons GC, Wilson KM, Gallardo DC, Isanogle KA, Robinson CM, Mendoza A, Heske CM, Chen JQ, Luo X, Kelly AE, Difilippantinio S, Robey RW, Thomas CJ, Sackett DL, Morrison DK, Randazzo PA, Jenkins LMM, Yohe ME. Kowalczyk JT, et al. Among authors: sackett dl. Mol Cancer Ther. 2021 Feb;20(2):307-319. doi: 10.1158/1535-7163.MCT-20-0525. Epub 2020 Nov 6. Mol Cancer Ther. 2021. PMID: 33158997 Free PMC article.

4

Evidence for microtubule target engagement in tumors of patients receiving ixabepilone.

Zhuang SH, Hung YE, Hung L, Robey RW, Sackett DL, Linehan WM, Bates SE, Fojo T, Poruchynsky MS. Zhuang SH, et al. Among authors: sackett dl. Clin Cancer Res. 2007 Dec 15;13(24):7480-6. doi: 10.1158/1078-0432.CCR-06-2883. Clin Cancer Res. 2007. PMID: 18094432 Clinical Trial.

5

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells.

Giannakakou P, Gussio R, Nogales E, Downing KH, Zaharevitz D, Bollbuck B, Poy G, Sackett D, Nicolaou KC, Fojo T. Giannakakou P, et al. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2904-9. doi: 10.1073/pnas.040546297. Proc Natl Acad Sci U S A. 2000. PMID: 10688884 Free PMC article.

6

Inhibitors targeting mitosis: tales of how great drugs against a promising target were brought down by a flawed rationale.

Komlodi-Pasztor E, Sackett DL, Fojo AT. Komlodi-Pasztor E, et al. Among authors: sackett dl. Clin Cancer Res. 2012 Jan 1;18(1):51-63. doi: 10.1158/1078-0432.CCR-11-0999. Clin Cancer Res. 2012. PMID: 22215906 Review.

7

FR901228 causes mitotic arrest but does not alter microtubule polymerization.

Sandor V, Robbins AR, Robey R, Myers T, Sausville E, Bates SE, Sackett DL. Sandor V, et al. Among authors: sackett dl. Anticancer Drugs. 2000 Jul;11(6):445-54. doi: 10.1097/00001813-200007000-00005. Anticancer Drugs. 2000. PMID: 11001385

8

Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin.

Sackett DL. Sackett DL. Pharmacol Ther. 1993 Aug;59(2):163-228. doi: 10.1016/0163-7258(93)90044-e. Pharmacol Ther. 1993. PMID: 8278462 Review.

9

A thalidomide analogue with in vitro antiproliferative, antimitotic, and microtubule-stabilizing activities.

Li PK, Pandit B, Sackett DL, Hu Z, Zink J, Zhi J, Freeman D, Robey RW, Werbovetz K, Lewis A, Li C. Li PK, et al. Among authors: sackett dl. Mol Cancer Ther. 2006 Feb;5(2):450-6. doi: 10.1158/1535-7163.MCT-05-0254. Mol Cancer Ther. 2006. PMID: 16505120

10

Microtubule-disrupting chemotherapeutics result in enhanced proteasome-mediated degradation and disappearance of tubulin in neural cells.

Huff LM, Sackett DL, Poruchynsky MS, Fojo T. Huff LM, et al. Among authors: sackett dl. Cancer Res. 2010 Jul 15;70(14):5870-9. doi: 10.1158/0008-5472.CAN-09-4281. Epub 2010 Jun 29. Cancer Res. 2010. PMID: 20587529 Free PMC article.

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