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SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model.
Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):665-71. doi: 10.1161/ATVBAHA.107.158030. Epub 2008 Jan 17.
Arterioscler Thromb Vasc Biol. 2008.
PMID: 18202322
Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).
Singh J, Chuaqui CE, Boriack-Sjodin PA, Lee WC, Pontz T, Corbley MJ, Cheung HK, Arduini RM, Mead JN, Newman MN, Papadatos JL, Bowes S, Josiah S, Ling LE.
Singh J, et al. Among authors: papadatos jl.
Bioorg Med Chem Lett. 2003 Dec 15;13(24):4355-9. doi: 10.1016/j.bmcl.2003.09.028.
Bioorg Med Chem Lett. 2003.
PMID: 14643325
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Adopting a practical statistical approach for evaluating assay agreement in drug discovery.
Sun D, Whitty A, Papadatos J, Newman M, Donnelly J, Bowes S, Josiah S.
Sun D, et al.
J Biomol Screen. 2005 Aug;10(5):508-16. doi: 10.1177/1087057105275725.
J Biomol Screen. 2005.
PMID: 16093560
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