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A multiplexed siRNA screening strategy to identify genes in the PARP pathway.
Stec E, Locco L, Szymanski S, Bartz SR, Toniatti C, Needham RH, Palmieri A, Carleton M, Cleary MA, Jackson AL, Linsley PS, Strulovici B, Ferrer M, Santini F. Stec E, et al. Among authors: locco l. J Biomol Screen. 2012 Dec;17(10):1316-28. doi: 10.1177/1087057112453071. Epub 2012 Jul 10. J Biomol Screen. 2012. PMID: 22786893
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.
Bartz SR, Zhang Z, Burchard J, Imakura M, Martin M, Palmieri A, Needham R, Guo J, Gordon M, Chung N, Warrener P, Jackson AL, Carleton M, Oatley M, Locco L, Santini F, Smith T, Kunapuli P, Ferrer M, Strulovici B, Friend SH, Linsley PS. Bartz SR, et al. Among authors: locco l. Mol Cell Biol. 2006 Dec;26(24):9377-86. doi: 10.1128/MCB.01229-06. Epub 2006 Sep 25. Mol Cell Biol. 2006. PMID: 17000754 Free PMC article.
Prospective Assessment of Virtual Screening Heuristics Derived Using a Novel Fusion Score.
Pertusi DA, O'Donnell G, Homsher MF, Solly K, Patel A, Stahler SL, Riley D, Finley MF, Finger EN, Adam GC, Meng J, Bell DJ, Zuck PD, Hudak EM, Weber MJ, Nothstein JE, Locco L, Quinn C, Amoss A, Squadroni B, Hartnett M, Heo MR, White T, May SA, Boots E, Roberts K, Cocchiarella P, Wolicki A, Kreamer A, Kutchukian PS, Wassermann AM, Uebele VN, Glick M, Rusinko A 3rd, Culberson JC. Pertusi DA, et al. Among authors: locco l. SLAS Discov. 2017 Sep;22(8):995-1006. doi: 10.1177/2472555217706058. Epub 2017 Apr 20. SLAS Discov. 2017. PMID: 28426940 Free article.
The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands.
Wilkening RR, Ratcliffe RW, Tynebor EC, Wildonger KJ, Fried AK, Hammond ML, Mosley RT, Fitzgerald PM, Sharma N, McKeever BM, Nilsson S, Carlquist M, Thorsell A, Locco L, Katz R, Frisch K, Birzin ET, Wilkinson HA, Mitra S, Cai S, Hayes EC, Schaeffer JM, Rohrer SP. Wilkening RR, et al. Among authors: locco l. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3489-94. doi: 10.1016/j.bmcl.2006.03.098. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16632357
6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.
Sun W, Cama LD, Birzin ET, Warrier S, Locco L, Mosley R, Hammond ML, Rohrer SP. Sun W, et al. Among authors: locco l. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1468-72. doi: 10.1016/j.bmcl.2005.12.057. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16412638
11 results