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Newly identified genetic risk variants for celiac disease related to the immune response.
Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R, Takeuchi F, McLaren WM, Holmes GK, Howdle PD, Walters JR, Sanders DS, Playford RJ, Trynka G, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA, Wapenaar MC, Deloukas P, McGinnis R, McManus R, Wijmenga C, van Heel DA. Hunt KA, et al. Among authors: trimble v. Nat Genet. 2008 Apr;40(4):395-402. doi: 10.1038/ng.102. Epub 2008 Mar 2. Nat Genet. 2008. PMID: 18311140 Free PMC article.
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.
Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C. Trynka G, et al. Among authors: trimble v. Gut. 2009 Aug;58(8):1078-83. doi: 10.1136/gut.2008.169052. Epub 2009 Feb 24. Gut. 2009. PMID: 19240061
Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci.
Coleman C, Quinn EM, Ryan AW, Conroy J, Trimble V, Mahmud N, Kennedy N, Corvin AP, Morris DW, Donohoe G, O'Morain C, MacMathuna P, Byrnes V, Kiat C, Trynka G, Wijmenga C, Kelleher D, Ennis S, Anney RJ, McManus R. Coleman C, et al. Among authors: trimble v. Eur J Hum Genet. 2016 Feb;24(2):291-7. doi: 10.1038/ejhg.2015.87. Epub 2015 Apr 29. Eur J Hum Genet. 2016. PMID: 25920553 Free PMC article.
The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.
Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PW, O'Donoghue D, O'Sullivan M, O'Morain C, Mahmud N, Wikström AC, Kelleher D, McManus R. Dring MM, et al. Among authors: trimble vi. Gastroenterology. 2006 Feb;130(2):341-8; quiz 592. doi: 10.1053/j.gastro.2005.12.008. Gastroenterology. 2006. PMID: 16472590
Changes in Presentation of Celiac Disease in Ireland From the 1960s to 2015.
Dominguez Castro P, Harkin G, Hussey M, Christopher B, Kiat C, Liong Chin J, Trimble V, McNamara D, MacMathuna P, Egan B, Ryan B, Kevans D, Farrell R, Byrnes V, Mahmud N, McManus R. Dominguez Castro P, et al. Among authors: trimble v. Clin Gastroenterol Hepatol. 2017 Jun;15(6):864-871.e3. doi: 10.1016/j.cgh.2016.11.018. Epub 2016 Dec 31. Clin Gastroenterol Hepatol. 2017. PMID: 28043932
Prevalence of coexisting autoimmune thyroidal diseases in coeliac disease is decreasing.
Castro PD, Harkin G, Hussey M, Christopher B, Kiat C, Chin JL, Trimble V, McNamara D, MacMathuna P, Egan B, Ryan B, Kevans D, Abuzakouk M, Farrell R, Feighery C, Byrnes V, Mahmud N, McManus R. Castro PD, et al. Among authors: trimble v. United European Gastroenterol J. 2020 Mar;8(2):148-156. doi: 10.1177/2050640619899225. Epub 2020 Jan 7. United European Gastroenterol J. 2020. PMID: 32213077 Free PMC article.
21 results