Frankel AE - Search Results

1

Mitogen-activated protein kinase kinase signaling promotes growth and vascularization of fibrosarcoma.

Ding Y, Boguslawski EA, Berghuis BD, Young JJ, Zhang Z, Hardy K, Furge K, Kort E, Frankel AE, Hay RV, Resau JH, Duesbery NS. Ding Y, et al. Among authors: frankel ae. Mol Cancer Ther. 2008 Mar;7(3):648-58. doi: 10.1158/1535-7163.MCT-07-2229. Epub 2008 Mar 4. Mol Cancer Ther. 2008. PMID: 18319331

2

BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin.

Abi-Habib RJ, Urieto JO, Liu S, Leppla SH, Duesbery NS, Frankel AE. Abi-Habib RJ, et al. Among authors: frankel ae. Mol Cancer Ther. 2005 Sep;4(9):1303-10. doi: 10.1158/1535-7163.MCT-05-0145. Mol Cancer Ther. 2005. PMID: 16170021

3

Anthrax lethal toxin inhibits growth of and vascular endothelial growth factor release from endothelial cells expressing the human herpes virus 8 viral G protein coupled receptor.

Depeille P, Young JJ, Boguslawski EA, Berghuis BD, Kort EJ, Resau JH, Frankel AE, Duesbery NS. Depeille P, et al. Among authors: frankel ae. Clin Cancer Res. 2007 Oct 1;13(19):5926-34. doi: 10.1158/1078-0432.CCR-07-0732. Clin Cancer Res. 2007. PMID: 17908989

4

Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma.

Alfano RW, Leppla SH, Liu S, Bugge TH, Ortiz JM, Lairmore TC, Duesbery NS, Mitchell IC, Nwariaku F, Frankel AE. Alfano RW, et al. Among authors: frankel ae. Mol Cancer Ther. 2010 Jan;9(1):190-201. doi: 10.1158/1535-7163.MCT-09-0694. Epub 2010 Jan 6. Mol Cancer Ther. 2010. PMID: 20053778 Free PMC article.

5

Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice.

Abi-Habib RJ, Singh R, Leppla SH, Greene JJ, Ding Y, Berghuis B, Duesbery NS, Frankel AE. Abi-Habib RJ, et al. Among authors: frankel ae. Clin Cancer Res. 2006 Dec 15;12(24):7437-43. doi: 10.1158/1078-0432.CCR-06-2019. Clin Cancer Res. 2006. PMID: 17189417

6

Potent inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin: implications for broad anti-tumor efficacy.

Alfano RW, Leppla SH, Liu S, Bugge TH, Duesbery NS, Frankel AE. Alfano RW, et al. Among authors: frankel ae. Cell Cycle. 2008 Mar 15;7(6):745-9. doi: 10.4161/cc.7.6.5627. Epub 2008 Jan 18. Cell Cycle. 2008. PMID: 18245947 Review.

7

Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.

Alfano RW, Leppla SH, Liu S, Bugge TH, Herlyn M, Smalley KS, Bromberg-White JL, Duesbery NS, Frankel AE. Alfano RW, et al. Among authors: frankel ae. Mol Cancer Ther. 2008 May;7(5):1218-26. doi: 10.1158/1535-7163.MCT-08-0024. Mol Cancer Ther. 2008. PMID: 18483309 Free PMC article.

8

Matrix metalloproteinase-activated anthrax lethal toxin inhibits endothelial invasion and neovasculature formation during in vitro morphogenesis.

Alfano RW, Leppla SH, Liu S, Bugge TH, Meininger CJ, Lairmore TC, Mulne AF, Davis SH, Duesbery NS, Frankel AE. Alfano RW, et al. Among authors: frankel ae. Mol Cancer Res. 2009 Apr;7(4):452-61. doi: 10.1158/1541-7786.MCR-08-0451. Mol Cancer Res. 2009. PMID: 19372576 Free PMC article.

9

Novel protein targeted therapy of metastatic melanoma.

Frankel AE, Koo HM, Leppla SH, Duesbery NS, Vande Woude GF. Frankel AE, et al. Curr Pharm Des. 2003;9(25):2060-6. doi: 10.2174/1381612033454162. Curr Pharm Des. 2003. PMID: 14552326 Review.

10

The systemic administration of lethal toxin achieves a growth delay of human melanoma and neuroblastoma xenografts: assessment of receptor contribution.

Rouleau C, Menon K, Boutin P, Guyre C, Yoshida H, Kataoka S, Perricone M, Shankara S, Frankel AE, Duesbery NS, Vande Woude G, Biemann HP, Teicher BA. Rouleau C, et al. Among authors: frankel ae. Int J Oncol. 2008 Apr;32(4):739-48. Int J Oncol. 2008. PMID: 18360701

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