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Page 1
Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors.
Edmondson SD, Wei L, Xu J, Shang J, Xu S, Pang J, Chaudhary A, Dean DC, He H, Leiting B, Lyons KA, Patel RA, Patel SB, Scapin G, Wu JK, Beconi MG, Thornberry NA, Weber AE. Edmondson SD, et al. Among authors: dean dc. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2409-13. doi: 10.1016/j.bmcl.2008.02.050. Epub 2008 Feb 26. Bioorg Med Chem Lett. 2008. PMID: 18331795
Transport of the dipeptidyl peptidase-4 inhibitor sitagliptin by human organic anion transporter 3, organic anion transporting polypeptide 4C1, and multidrug resistance P-glycoprotein.
Chu XY, Bleasby K, Yabut J, Cai X, Chan GH, Hafey MJ, Xu S, Bergman AJ, Braun MP, Dean DC, Evers R. Chu XY, et al. Among authors: dean dc. J Pharmacol Exp Ther. 2007 May;321(2):673-83. doi: 10.1124/jpet.106.116517. Epub 2007 Feb 21. J Pharmacol Exp Ther. 2007. PMID: 17314201
Synthesis of the first sulfur-35-labeled hERG radioligand.
Raab CE, Butcher JW, Connolly TM, Karczewski J, Yu NX, Staskiewicz SJ, Liverton N, Dean DC, Melillo DG. Raab CE, et al. Among authors: dean dc. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1692-5. doi: 10.1016/j.bmcl.2005.12.021. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377185
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).
Garcia-Calvo M, Lisnock J, Bull HG, Hawes BE, Burnett DA, Braun MP, Crona JH, Davis HR Jr, Dean DC, Detmers PA, Graziano MP, Hughes M, Macintyre DE, Ogawa A, O'neill KA, Iyer SP, Shevell DE, Smith MM, Tang YS, Makarewicz AM, Ujjainwalla F, Altmann SW, Chapman KT, Thornberry NA. Garcia-Calvo M, et al. Among authors: dean dc. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8132-7. doi: 10.1073/pnas.0500269102. Epub 2005 May 31. Proc Natl Acad Sci U S A. 2005. PMID: 15928087 Free PMC article.
Ivermectin and nodulisporic acid receptors in Drosophila melanogaster contain both gamma-aminobutyric acid-gated Rdl and glutamate-gated GluCl alpha chloride channel subunits.
Ludmerer SW, Warren VA, Williams BS, Zheng Y, Hunt DC, Ayer MB, Wallace MA, Chaudhary AG, Egan MA, Meinke PT, Dean DC, Garcia ML, Cully DF, Smith MM. Ludmerer SW, et al. Among authors: dean dc. Biochemistry. 2002 May 21;41(20):6548-60. doi: 10.1021/bi015920o. Biochemistry. 2002. PMID: 12009920
260 results