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Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs.
Urban TJ, Shen Y, Stolz A, Chalasani N, Fontana RJ, Rochon J, Ge D, Shianna KV, Daly AK, Lucena MI, Nelson MR, Molokhia M, Aithal GP, Floratos A, Pe'er I, Serrano J, Bonkovsky H, Davern TJ, Lee WM, Navarro VJ, Talwalkar JA, Goldstein DB, Watkins PB; Drug-Induced Liver Injury Network; DILIGEN; EUDRAGENE; Spanish DILI Registry; International Serious Adverse Events Consortium. Urban TJ, et al. Among authors: molokhia m. Pharmacogenet Genomics. 2012 Nov;22(11):784-95. doi: 10.1097/FPC.0b013e3283589a76. Pharmacogenet Genomics. 2012. PMID: 22968431 Free PMC article.
Suboptimal gastroprotective coverage of NSAID use and the risk of upper gastrointestinal bleeding and ulcers: an observational study using three European databases.
van Soest EM, Valkhoff VE, Mazzaglia G, Schade R, Molokhia M, Goldstein JL, Hernández-Díaz S, Trifirò G, Dieleman JP, Kuipers EJ, Sturkenboom MC. van Soest EM, et al. Among authors: molokhia m. Gut. 2011 Dec;60(12):1650-9. doi: 10.1136/gut.2011.239848. Epub 2011 Jun 2. Gut. 2011. PMID: 21636644
Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing.
Floyd JS, Bloch KM, Brody JA, Maroteau C, Siddiqui MK, Gregory R, Carr DF, Molokhia M, Liu X, Bis JC, Ahmed A, Liu X, Hallberg P, Yue QY, Magnusson PKE, Brisson D, Wiggins KL, Morrison AC, Khoury E, McKeigue P, Stricker BH, Lapeyre-Mestre M, Heckbert SR, Gallagher AM, Chinoy H, Gibbs RA, Bondon-Guitton E, Tracy R, Boerwinkle E, Gaudet D, Conforti A, van Staa T, Sitlani CM, Rice KM, Maitland-van der Zee AH, Wadelius M, Morris AP, Pirmohamed M, Palmer CAN, Psaty BM, Alfirevic A; PREDICTION-ADR Consortium and EUDRAGENE. Floyd JS, et al. Among authors: molokhia m. PLoS One. 2019 Jun 26;14(6):e0218115. doi: 10.1371/journal.pone.0218115. eCollection 2019. PLoS One. 2019. PMID: 31242253 Free PMC article.
HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury.
Nicoletti P, Werk AN, Sawle A, Shen Y, Urban TJ, Coulthard SA, Bjornsson ES, Cascorbi I, Floratos A, Stammschulte T, Gundert-Remy U, Nelson MR, Aithal GP, Daly AK; International Drug-induced Liver Injury Consortium. Nicoletti P, et al. Pharmacogenet Genomics. 2016 May;26(5):218-24. doi: 10.1097/FPC.0000000000000209. Pharmacogenet Genomics. 2016. PMID: 26959717
Cyclo-oxygenase-2 inhibitors or nonselective NSAIDs plus gastroprotective agents: what to prescribe in daily clinical practice?
Masclee GM, Valkhoff VE, van Soest EM, Schade R, Mazzaglia G, Molokhia M, Trifirò G, Goldstein JL, Hernández-Díaz S, Kuipers EJ, Sturkenboom MC. Masclee GM, et al. Among authors: molokhia m. Aliment Pharmacol Ther. 2013 Jul;38(2):178-89. doi: 10.1111/apt.12348. Epub 2013 May 28. Aliment Pharmacol Ther. 2013. PMID: 23710837 Free PMC article.
Genetic variants associated with antithyroid drug-induced agranulocytosis: a genome-wide association study in a European population.
Hallberg P, Eriksson N, Ibañez L, Bondon-Guitton E, Kreutz R, Carvajal A, Lucena MI, Ponce ES, Molokhia M, Martin J, Axelsson T, Yue QY, Magnusson PK, Wadelius M; EuDAC collaborators. Hallberg P, et al. Among authors: molokhia m. Lancet Diabetes Endocrinol. 2016 Jun;4(6):507-16. doi: 10.1016/S2213-8587(16)00113-3. Epub 2016 May 3. Lancet Diabetes Endocrinol. 2016. PMID: 27157822 Free article.
Use of azithromycin and risk of ventricular arrhythmia.
Trifirò G, de Ridder M, Sultana J, Oteri A, Rijnbeek P, Pecchioli S, Mazzaglia G, Bezemer I, Garbe E, Schink T, Poluzzi E, Frøslev T, Molokhia M, Diemberger I, Sturkenboom MCJM. Trifirò G, et al. Among authors: molokhia m. CMAJ. 2017 Apr 18;189(15):E560-E568. doi: 10.1503/cmaj.160355. CMAJ. 2017. PMID: 28420680 Free PMC article.
202 results