Edwards S - Search Results

1

Variations in DNA elucidate molecular networks that cause disease.

Chen Y, Zhu J, Lum PY, Yang X, Pinto S, MacNeil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE. Chen Y, et al. Among authors: edwards s. Nature. 2008 Mar 27;452(7186):429-35. doi: 10.1038/nature06757. Epub 2008 Mar 16. Nature. 2008. PMID: 18344982 Free PMC article.

2

An integrative genomics approach to infer causal associations between gene expression and disease.

Schadt EE, Lamb J, Yang X, Zhu J, Edwards S, Guhathakurta D, Sieberts SK, Monks S, Reitman M, Zhang C, Lum PY, Leonardson A, Thieringer R, Metzger JM, Yang L, Castle J, Zhu H, Kash SF, Drake TA, Sachs A, Lusis AJ. Schadt EE, et al. Among authors: edwards s. Nat Genet. 2005 Jul;37(7):710-7. doi: 10.1038/ng1589. Epub 2005 Jun 19. Nat Genet. 2005. PMID: 15965475 Free PMC article.

3

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels.

Cervino AC, Li G, Edwards S, Zhu J, Laurie C, Tokiwa G, Lum PY, Wang S, Castellani LW, Lusis AJ, Carlson S, Sachs AB, Schadt EE. Cervino AC, et al. Among authors: edwards s. Genomics. 2005 Nov;86(5):505-17. doi: 10.1016/j.ygeno.2005.07.010. Epub 2005 Aug 29. Genomics. 2005. PMID: 16126366

4

Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits.

Mehrabian M, Allayee H, Stockton J, Lum PY, Drake TA, Castellani LW, Suh M, Armour C, Edwards S, Lamb J, Lusis AJ, Schadt EE. Mehrabian M, et al. Among authors: edwards s. Nat Genet. 2005 Nov;37(11):1224-33. doi: 10.1038/ng1619. Epub 2005 Oct 2. Nat Genet. 2005. PMID: 16200066

5

Experimental annotation of the human genome using microarray technology.

Shoemaker DD, Schadt EE, Armour CD, He YD, Garrett-Engele P, McDonagh PD, Loerch PM, Leonardson A, Lum PY, Cavet G, Wu LF, Altschuler SJ, Edwards S, King J, Tsang JS, Schimmack G, Schelter JM, Koch J, Ziman M, Marton MJ, Li B, Cundiff P, Ward T, Castle J, Krolewski M, Meyer MR, Mao M, Burchard J, Kidd MJ, Dai H, Phillips JW, Linsley PS, Stoughton R, Scherer S, Boguski MS. Shoemaker DD, et al. Among authors: edwards s. Nature. 2001 Feb 15;409(6822):922-7. doi: 10.1038/35057141. Nature. 2001. PMID: 11237012

6

An integrative genomics approach to the reconstruction of gene networks in segregating populations.

Zhu J, Lum PY, Lamb J, GuhaThakurta D, Edwards SW, Thieringer R, Berger JP, Wu MS, Thompson J, Sachs AB, Schadt EE. Zhu J, et al. Among authors: edwards sw. Cytogenet Genome Res. 2004;105(2-4):363-74. doi: 10.1159/000078209. Cytogenet Genome Res. 2004. PMID: 15237224

7

Cis-regulatory variations: a study of SNPs around genes showing cis-linkage in segregating mouse populations.

GuhaThakurta D, Xie T, Anand M, Edwards SW, Li G, Wang SS, Schadt EE. GuhaThakurta D, et al. Among authors: edwards sw. BMC Genomics. 2006 Sep 15;7:235. doi: 10.1186/1471-2164-7-235. BMC Genomics. 2006. PMID: 16978413 Free PMC article.

8

Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network.

Tu Z, Argmann C, Wong KK, Mitnaul LJ, Edwards S, Sach IC, Zhu J, Schadt EE. Tu Z, et al. Among authors: edwards s. Genome Res. 2009 Jun;19(6):1057-67. doi: 10.1101/gr.087890.108. Epub 2009 Mar 4. Genome Res. 2009. PMID: 19261841 Free PMC article.

9

Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments.

Johnson JM, Edwards S, Shoemaker D, Schadt EE. Johnson JM, et al. Among authors: edwards s. Trends Genet. 2005 Feb;21(2):93-102. doi: 10.1016/j.tig.2004.12.009. Trends Genet. 2005. PMID: 15661355 Review.

10

Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences.

Su WL, Modrek B, GuhaThakurta D, Edwards S, Shah JK, Kulkarni AV, Russell A, Schadt EE, Johnson JM, Castle JC. Su WL, et al. Among authors: edwards s. BMC Genomics. 2008 Jun 4;9:273. doi: 10.1186/1471-2164-9-273. BMC Genomics. 2008. PMID: 18533039 Free PMC article.

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