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4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.
Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. Among authors: celanire s. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114
Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
Célanire S, Wijtmans M, Christophe B, Collart P, de Esch I, Dassesse D, Delaunoy C, Denonne F, Durieu V, Gelens E, Gillard M, Lallemand B, Lamberty Y, Lebon F, Nicolas JM, Quéré L, Snip E, Vanbellinghen A, Van Houtvin N, Verbois V, Timmerman H, Talaga P, Leurs R, Provins L. Célanire S, et al. ChemMedChem. 2009 Jul;4(7):1063-8. doi: 10.1002/cmdc.200900055. ChemMedChem. 2009. PMID: 19405064
Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
Denonne F, Atienzar F, Célanire S, Christophe B, Delannois F, Delaunoy C, Delporte ML, Durieu V, Gillard M, Lallemand B, Lamberty Y, Lorent G, Vanbellinghen A, Van Houtvin N, Verbois V, Provins L. Denonne F, et al. Among authors: celanire s. ChemMedChem. 2010 Feb 1;5(2):206-12. doi: 10.1002/cmdc.200900446. ChemMedChem. 2010. PMID: 20043314 No abstract available.
Lead optimization of thiazolo[5,4-c]piperidines: 3-cyclobutoxy linker as a key spacer for H(3)R inverse agonists.
Provins L, Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Demaude T, Durieu V, Gillard M, Hubert D, Lamberty Y, Lorent G, Valade A, Vanbellinghen A, Van Houtvin N. Provins L, et al. Among authors: celanire s. ChemMedChem. 2012 Dec;7(12):2087-92. doi: 10.1002/cmdc.201200406. Epub 2012 Oct 5. ChemMedChem. 2012. PMID: 23042668
Acetamide scanning around bicyclic thiazoles: SAR at the H₃ receptor.
Denonne F, Célanire S, Christophe B, Defays S, Delaunoy C, Delporte ML, Detrait E, Durieu V, Gillard M, Lamberty Y, Lorent G, Nicolas JM, Vanbellinghen A, Van Houtvin N, Provins L. Denonne F, et al. Among authors: celanire s. ChemMedChem. 2011 Sep 5;6(9):1559-65. doi: 10.1002/cmdc.201100248. Epub 2011 Jul 14. ChemMedChem. 2011. PMID: 21761567 No abstract available.
14 results